Expanded access for patients with cancer with RET activation who are ineligible for an ongoing selpercatinib (also known as LOXO-292) clinical trial or have other considerations that prevent access to selpercatinib through an existing clinical trial.
N/A for expanded access
Drug: Selpercatinib
Open-label expanded access
Other Name: LOXO-292
Inclusion Criteria:
- Diagnosis of cancer with RET activation, who are not eligible for an ongoing selpercatinib clinical trial and are medically suitable for treatment with selpercatinib
Exclusion Criteria:
- Currently enrolled in an ongoing clinical study of selpercatinib or another RET inhibitor
Cancer Treatment Centers of America
Goodyear, Arizona, 85338
Investigator: Ashish Sangal, MD
Investigator: Ashish Sangal, MD
Mayo Clinic Hospital
Scottsdale, Arizona, 85054
Investigator: Nina Karlin
Investigator: Nina Karlin, MD
City of Hope
Duarte, California, 91010
Investigator: Erminia Massarelli, MD, PhD
Investigator: Erminia Massarelli, MD, PhD
UC San Diego Moores Cancer Center
La Jolla, California, 92093
Investigator: Lyudmila Bazhenova, MD
Investigator: Lyudmia Bazhenova, MD
UCI Health - Chao Family Comprehensive Cancer Center
Orange, California, 92868
Investigator: Viola Zhu, MD
Investigator: Viola Zhu, MD
UCSF Helen Diller Family Comprehensive Cancer Center
San Francisco, California, 94158
Investigator: Alain Algazi, MD
Investigator: Alain Algazi, MD
Lundquist Institute for Biomedical Innovation at Harbor UCLA Medical Center
Torrance, California, 90502
Investigator: Mykola Onyshchenko, MD
Investigator: Mykola Onshchenko, MD
Kaiser Permanente Medical Center
Vallejo, California, 94589
Investigator: Jennifer Suga, MD
Investigator: Jennifer Suga, MD
Memorial Regional Hospital
Hollywood, Florida, 33021
Investigator: Luis Raez, MD
Investigator: Luis Raez, MD
Mayo Clinic Hospital
Jacksonville, Florida, 32224
Investigator: Victor Bernet, MD
Investigator: Victor Bernet, MD
AdventHealth Orlando
Orlando, Florida, 32804
Investigator: Mark Socinski, MD
Investigator: Mark Socinski, MD
Tallahassee Memorial Hospital
Tallahassee, Florida, 32308
Investigator: Karen Russell, MD
Investigator: Karen Russell, MD
University Cancer and Blood Center
Athens, Georgia, 30607
Investigator: Petros Nikolinakos, MD
Investigator: Petros Nikolinakos, MD
Emory University
Atlanta, Georgia, 30322
Investigator: Taofeek Owonikoko, MD
Investigator: Taofeek Owonikoko, MD
Cancer Treatment Centers of America, Chicago
Chicago, Illinois, 60099
Investigator: Eugene Ahn, MD
Investigator: Eugene Ahn, MD
University of Chicago Medical Center
Chicago, Illinois, 60637
Investigator: Christine Bestvina, MD
Investigator: Christine Bestvina, MD
Massachusetts General Hospital
Boston, Massachusetts, 02114
Investigator: Lori Wirth, MD
Investigator: Lori Wirth, MD
Dana-Farber Cancer Institute
Boston, Massachusetts, 02215
Investigator: Geoffrey Oxnard, MD
Investigator: Geoffrey Oxnard, MD
University of Michigan
Ann Arbor, Michigan, 48109
Investigator: Francis Worden, MD
Investigator: Francis Worden, MD
START Midwest
Grand Rapids, Michigan, 49546
Investigator: Nehal Lakhani, MD
Investigator: Nehal Lakhani, MD
Mayo Clinic Hospital
Rochester, Minnesota, 55905
Investigator: John Morris, MD
Investigator: John Morris, MD
Comprehensive Cancer Centers of Nevada
Las Vegas, Nevada, 89169
Investigator: Fadi Braiteh, MD
Investigator: Fadi Braiteh, MD
Memorial Sloan Kettering Cancer Center
New York, New York, 10065
Investigator: Alexander Drilon, MD
Investigator: Alexander Drilon, MD
Cleveland Clinic
Cleveland, Ohio, 44195
Investigator: Nathan Pennell, MD
Investigator: Nathan Pennell, MD
JamesCare at Martha Morehouse Medical Plaza
Columbus, Ohio, 43210
Investigator: Manisha Shah, MD
Investigator: Manisah Shah, MD
Cancer Treatment Centers of America
Tulsa, Oklahoma, 74133
Investigator: Theodore Pollock, MD
Investigator: Theodore Pollock, MD
University of Pennsylvania, Perelman School of Medicine
Philadelphia, Pennsylvania, 19104
Investigator: Marcia Brose, MD, PhD
Investigator: Marcia Brose, MD, PhD
Cancer Treatment Centers of American, Philadelphia
Philadelphia, Pennsylvania, 19124
Investigator: Arturo Loaiza-Bonilla, MD
Investigator: Arturo Loaiza-Bonilla, MD
M.D. Anderson Cancer Center
Houston, Texas, 77030
Investigator: Vivek Subbiah, MD
Investigator: Vivek Subbiah, MD
Oncology Consultants
Houston, Texas, 77030
Investigator: Julio Peguero, MD
Investigator: Julio Peguero, MD
Virginia Cancer Specialists
Fairfax, Virginia, 22031
Investigator: Alexander Spira, MD
Investigator: Alexander Spira, MD
Patient Advocacy
888-406-9574
LoxoNPP@UBC.com
Patient Advocacy
855-RET-4-292 (855-738-4292)
clinicaltrials@loxooncology.com
Jen Kherani, MD
Study Director
Loxo Oncology