Official Title
Expanded Access Protocol to Provide Lumasiran to Patients With Primary Hyperoxaluria Type 1
Brief Summary

The purpose of this study is to provide expanded access to lumasiran for adults andpediatric patients with Primary Hyperoxaluria Type 1 (PH1),

Detailed Description

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Approved for marketing
Individual Patients
Treatment IND/Protocol
Primary Hyperoxaluria

Drug: Lumasiran

Lumasiran administered as a subcutaneous (SC) injection
Other Name: ALN-GO1

Eligibility Criteria

Inclusion Criteria:

- Documented diagnosis of Primary Hyperoxaluria Type 1

Exclusion Criteria:

- Clinically significant health concerns (with the exception of PH1)

- Received an investigational agent within 30 days before the first dose of lumasiran
or are in follow-up of another clinical study

- Previously or currently participating in lumasiran clinical study

- History of liver transplant

Eligibility Gender
Eligibility Age
Minimum: N/A ~ Maximum: N/A

Medical Director, Study Director
Alnylam Pharmaceuticals

Alnylam Pharmaceuticals
NCT Number
Primary Hyperoxaluria
Kidney Diseases
Urologic Diseases
Metabolism, Inborn Errors
Genetic Diseases, Inborn
Metabolic Diseases
RNA Therapeutic
MeSH Terms
Hyperoxaluria, Primary