The COVID-19 pandemic dramatically increased health disparities. In the United States,>79 million have been infected with SARS-CoV-2 and >900,000 died, but cases and deathsdisproportionately affect underserved populations. Novel treatments early in disease maytransform the pandemic's course, but strategies that address disparities in timelytesting and treatment access are essential to maximize impact. To address profoundCOVID-19 disparities, testing strategies should be developed together withcommunity-trusted organizations in high-need areas identified with risk assessmentstrategies to address barriers to test access, determine infrastructure needs, andposition testing to promote timely access, awareness and education, and engagement withhealth systems and local resources. The You & Me Healthy (YMH) Toolkit is a guide todevelop academic-community partnerships in underserved communities in response to publichealth threats. In this application, the investigators will evaluate the toolkit's rolein preparing community-based test distribution and test and treat responses to the nextphase of the COVID-19 pandemic in underserved populations.Widening COVID-19 health and education disparities will have a profound impact forgenerations, with infections and deaths disproportionally affecting underservedpopulations that have been historically marginalized. Inequitable risk of COVID-19infection and unequal access to care have been observed among lower socio-economic andracial/ethnic minorities with higher hospitalization rates, lower recovery rates, andhigher mortality. As outlined at the core of Public Health 3.0, local communities willlead the charge in taking public health to the next level and ensure its continuedsuccess. Within this framework community members serve as partners for research, and bothcommunity and research resources are leveraged to address social, environmental, andeconomic conditions that magnify health disparities in communities. Community engagementis increasingly being recognized as enhancing research quality and relevance to publichealth practice. Benefits of engaging communities have been reported in all stages ofresearch including 1) identifying key research questions based on firsthand knowledge andinsight from the field; 2) designing informed consent processes and research protocolsthat meet the needs of the community; 3) adapting public health interventions to becontext-relevant; 4) identifying implementation processes to promote public healthintervention feasibility and adoption; and 5) disseminating research results to makeinformation more accessible.