Acute viral respiratory infections are a major public health problem, as they causemortality especially in pediatric patients, over 65 and those with co-morbidities. Themost frequently responsible viruses are: Influenza A and B, Respiratory Syncytial Virus,Adenovirus, Parainfluenza Virus, Metapneumovirus, Rhinovirus and SARS-CoV-2. By comparingclinical data and laboratory diagnosis among all categories of patients at greatest risk,it is possible to define the symptoms associated with the pathogen and establish whichetiological agents could be able to cause clinical pictures characteristics of a giventype of patient. The study will also provide information on the potential role thatsimultaneously detected pathogens may play in determining the severity of the clinicalpicture. In addition, the results will allow to deepen the changes in seasonality andspread of different respiratory viruses associated with the COVID-19 pandemic.
The aim of the study is:
1. Calculate the percentage of positive cases during 2018-2023.
2. Association between the viral pathogens detected individually or in packaging in
respiratory material and: typology of symptomatology/clinical outcome; typology of
clinical signs detectable with objective/instrumental examinations; degree of
severity of clinical manifestation.
3. Reduction in the prescription of instrumental investigations (RX/ecoaddome) and
reduction in the prescription of empirical antibiotic therapy with amoxicillin or
amoxicillin and clavulanic acid in pediatric patients.
Inclusion Criteria:
- Adult and pediatric patients, of any age, with clinical diagnosis of acute
respiratory infections and with request for search of the main respiratory viruses
(FLUA, FLUB, VRS, AdV, PIV, MPV, RV and SARS-CoV-2)
- Obtaining informed consent where possible.
Exclusion Criteria:
- None
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bologna, Italy
Investigator: Liliana Gabrielli, MD
Contact: +390512144645
liliana.gabrielli@aosp.bo.it
Liliana Gabrielli, MD
+390512414645
liliana.gabrielli@aosp.bo.it
Giulia Piccirilli, PhD
giulia.piccirilli@aosp.bo.it