Inclusion Criteria:

The study will include volunteers who meet all the specified criteria:

1. Written informed consents to participate in the study, obtained from: the volunteer,
his/her parent or a legal guardian;

2. 12-17 years old teenagers (men and women);

3. A negative test result for COVID-19, determined by PCR or express method before the
introduction of the investigational medicinal product (IMP);

4. No COVID-19 during 6 months prior to the screening (according to the anamnesis);

5. No contact of the volunteer with COVID-19 patients for at least 14 days prior to
inclusion in the Study (according to the volunteer, his/her parent or a legal
guardian);

6. Consent to the use of effective methods of contraception during the entire period of
participation in the Study;

7. A negative pregnancy test based on the results of a urine test at a screening visit
(for women with preserved reproductive potential);

8. Negative test for the presence of narcotic and psychostimulants in the urine at the
screening visit;

8. Negative alcohol content test at the screening visit; 9. No history of pronounced
post-vaccination reactions or post-vaccination complications after the use of
immunobiological drugs (according to the anamnesis); 9. Absence of acute infectious
and/or respiratory diseases for at least 14 days prior to inclusion in the Study.

Exclusion Criteria:

Volunteers cannot be included in the study if there is at least one of the following
criteria for non-inclusion:

1. Any vaccination/immunization carried out within 30 days prior to inclusion in the
Study;

2. Therapy with steroids (with the exception of hormonal contraceptives and/or hormone
replacement therapy) and / or immunoglobulins or other blood products that did not
end 30 days before inclusion in the Study;

3. Therapy with any immunosuppressive drugs completed less than 3 months prior to
inclusion in the Study;

4. Acute coronary syndrome or stroke suffered less than one year prior to inclusion in
the Study;

5. Any immunodeficiency (for example, hereditary immunodeficiency, acquired
immunodeficiency syndrome [AIDS], etc.);

6. Infectious diseases (according to the anamnesis): history of HIV, hepatitis, active
form of syphilis at the time of screening; Tuberculosis; Active infection (with the
exception of onychomycosis), or any acute infection episode requiring treatment with
antibiotics intravenously for 4 weeks prior to screening or orally for 2 weeks prior
to screening; History (according to the anamnesis) of serious recurrent or chronic
infection, not listed above;

7. Extensive surgery within 4 weeks prior to screening;

8. Chronic autoimmune diseases or systemic collagenoses (according to the anamnesis),
requiring the prescription of immunosuppressive therapy;

9. Volunteers who have undergone organ transplantation, including bone-marrow
transplantation or peripheral blood stem cell transplantation and receive
immunosuppressive therapy;

10. Splenectomy (according to the anamnesis);

11. Volunteers with a previous or concomitant history of neoplasms (ICD codes C00-D09);

12. Burdened allergic anamnesis (record of anaphylactic shock, Quincke's edema,
polymorphic exudative eczema, serum sickness in the anamnesis), hypersensitivity or
allergic reactions to the administration of immunobiological drugs, known allergic
reactions to any of the components of the vaccine or vaccine containing similar
components, exacerbation of allergic diseases on the day of inclusion in the study;

13. Neutropenia (decrease in the absolute number of neutrophils less than 1000 cells /
mm3), agranulocytosis, significant blood loss, severe anemia (hemoglobin
concentration less than 80 g/l), thrombocytopenia (decrease in the absolute number
of platelets less than 50,000 cells/ mm3);

14. Anorexia, protein deficiency of any origin;

15. Volunteers with a BMI value in the range from -2 SD to +2 SD, according to their
age;

16. Extensive tattoos at the injection sites (deltoid muscle area), which do not allow
to assess the local reaction to the introduction of investigational medicinal
product (IMP);

17. Chronic diseases of the cardiovascular, bronchopulmonary, neuroendocrine systems, as
well as diseases of the gastrointestinal tract, liver, kidneys, muscle and
connective tissue in the stage of exacerbation or decompensation;

18. Presence of mental abnormalities (registered as psychiatrist's/narcologist's
patient);

19. Diseases, the presence of which, from the point of view of the research doctor, puts
the participant's health at risk in case of participation in the Study or
potentially complicates the interpretation of the results of the examination;

20. Family members of the staff of research centers directly involved in the research;

21. The subject's participation in any other clinical trial 90 days prior to the
screening;

22. Planned vaccination against COVID-19 with any vaccine, both in the framework of
other studies and civil circulation;

23. Vaccination against COVID-19 or transmitted coronavirus infection COVID-19 less than
6 months prior to the screening;

24. Female volunteers during pregnancy or lactation;

25. Inability to read in Russian; inability or unwillingness to understand the essence
of the Study. Any other conditions that limit the validity of obtaining informed
consent or may affect the ability of a volunteer to participate in the Study.