Inclusion Criteria:

1. Male and female participants 18 to 75 years of age, inclusive, at screening who are
overtly healthy as determined by medical evaluation, including medical history,
physical examination, laboratory tests, and standard 12-lead ECGs.

2. BMI of 17.5 to 32 kg/m2; and a total body weight >50 kg (110 lb).

3. Capable of giving signed informed consent.

4. Willing and able to comply with all scheduled visits, treatment plans, laboratory
tests, lifestyle considerations, and other study procedures.

Exclusion Criteria:

1. Evidence or history of clinically significant hematological, renal, endocrine,
pulmonary, gastrointestinal, cardiovascular, hepatic, psychiatric, neurological, or
allergic disease (including drug allergies, but excluding untreated, asymptomatic,
seasonal allergies at the time of dosing) and, in the judgment of the investigator,
would make the participant inappropriate for entry into this study. Any condition
possibly affecting drug absorption (eg, gastrectomy, cholecystectomy). History of
HIV infection, hepatitis B, or hepatitis C. Positive testing for HIV, HBsAg, or
HCVAb. Hepatitis B vaccination is allowed.

2. Any medical or psychiatric condition including recent (within the past year) or
active suicidal ideation/behavior or laboratory abnormality or other conditions that
may increase the risk of study participation or, in the investigator's judgment,
make the participant inappropriate for the study.

3. Use of prescription or nonprescription drugs and dietary and herbal supplements
within 28 days or 5 half-lives (whichever is longer) prior to the first dose of
study intervention.

4. Participation in other studies involving study intervention within 30 days or 5
half-lives (whichever is longer) prior to study entry. Previous administration with
an investigational product (drug or vaccine) within 30 days (or as determined by the
local requirement) or 5 half-lives preceding the first dose of study intervention
used in this study (whichever is longer). Participation in studies of other
investigational products (drug or vaccine) at any time during participation in this
study.

5. Active bleeding or risk of bleeding, including prior personal or family history of
abnormal bleeding, hereditary or acquired coagulation or platelet disorder or
abnormal coagulation test (PT/INR or PTT/aPTT) greater than the upper limit of
normal result at screening. Any significant risk factor for major bleeding, which
may include but is not limited to current or recent GI ulceration, presence of
malignant neoplasms at high risk of bleeding, recent brain or spinal injury, recent
brain, spinal, or ophthalmic surgery, recent intracranial hemorrhage, known or
suspected esophageal varices, arteriovenous malformations, vascular aneurysms, or
major intraspinal or intracerebral vascular abnormalities.

6. A positive urine drug test. A single repeat for positive drug screen may be allowed.

7. Pregnant or breastfeeding women or evidence of positive pregnancy test at screening
or Study Day -1.

8. Screening supine BP ≥ 140 mmHg (systolic) or ≥90 mmHg (diastolic) for participants
<60 years and ≥150/90 mmHg for participants ≥60 years old, following at least 5
minutes of supine rest. If systolic BP is ≥ 140 or 150 mmHg (based on age) or
diastolic BP is ≥ 90 mmHg, the BP should be repeated two more times, and the average
of the three BP values should be used to determine the participant's eligibility.

9. An eGFR of <75 mL/min as determined by CKD-EPI equation using Screat as described in
Section

10. Screening supine standard 12-lead ECG that demonstrates clinically relevant
abnormalities that may affect participant safety or interpretation of study results
(eg, QTcF > 450 msec or QRS interval > 120 msec, complete LBBB, signs of an acute or
indeterminate age myocardial infarction, ST-T interval changes suggestive of
myocardial ischemia, second- or third-degree AV block, or serious bradyarrhythmias
or tachyarrhythmias). If the uncorrected QT interval is > 450 msec, this interval
should be rate-corrected using the Fridericia method only, and the resulting QTcF
should be used for decision making and reporting. If QTcF exceeds 450 msec, or QRS
exceeds 120 msec, the ECG should be repeated twice, and the average of the three
QTcF or QRS values should be used to determine the participant's eligibility.
Computer-interpreted ECGs should be overread by a physician experienced in reading
ECGs before excluding a participant.

11. Participants with ANY of the following abnormalities in clinical laboratory tests at
screening, as assessed by the study-specific laboratory and confirmed by a single
repeat test, if deemed necessary:

AST or ALT ≥1.5 × ULN Total bilirubin ≥1.5 × ULN; participants with a history of
Gilbert's syndrome may have a direct bilirubin measured and would be eligible for
this study provided the direct bilirubin is ≤ ULN PT/INR or PTT/aPTT >1.0 × ULN

12. Participants who have recently underwent a surgery or invasive procedure prior to
study enrollment, or who anticipate requiring it during study conduct, are
ineligible for this study.

13. History of sensitivity reactions to dabigatran etexilate or any of the formulation
components of ibuzatrelvir or dabigatran etexilate.

14. Have any medical conditions, medical history, or are taking any medications that are
contraindicated in the dabigatran etexilate prescribing information.

15. History of alcohol abuse or repeated binge drinking and/or any other illicit drug
use or dependence within 6 months of screening. Binge drinking is defined as a
pattern of 5 (male) and 4 (female) or more alcoholic drinks in about 2 hours. As a
general rule, alcohol intake should not exceed 14 units per week (1 unit = 8 ounces
(240 mL) beer, 1 ounce (30 mL) of 40% spirit, or 3 ounces (90 mL) of wine).

16. Use of tobacco or nicotine-containing products in excess of the equivalent of 5
cigarettes per day or two chews of tobacco per day.

17. Investigator site staff directly involved in the conduct of the study and their
family members, site staff otherwise supervised by the investigator, and sponsor and
sponsor delegate employees directly involved in the conduct of the study and their
family members.