Inclusion Criteria

To be included in this study, each individual must satisfy all the following criteria:

1. Willing and able to give informed consent prior to study enrollment.

2. Medically stable adult male or female ≥ 65 years of age at Screening.

3. Participants may have 1 or more chronic medical diagnoses, but should be clinically
stable as assessed by:

1. Absence of changes in medical therapy in the past 2 months due to treatment
failure or toxicity;

2. Absence of medical events qualifying as SAEs within 3 months; and

3. Absence of known, current, and life-limiting diagnoses which render survival to
completion of the protocol unlikely in the opinion of the Investigator.

4. The participant has a body mass index (BMI) of 17 to 40 kg/m2, inclusive, at
Screening.

5. Participant must be able to receive an injection in the deltoid of at least 1 arm.

6. Able to attend study visits, comply with study requirements, and provide reliable
and complete reports of AEs.

7. Participants must have completed a primary vaccination series/booster against SARS
CoV-2 with an authorized/approved COVID-19 vaccine, with receipt of last dose of
authorized/approved vaccine (with or without boosters[s]) ≥ 8 weeks prior to
vaccination.

8. Female participants must be surgically sterile (ie, have undergone a hysterectomy,
bilateral tubal ligation, or bilateral oophorectomy) or postmenopausal (defined as
amenorrhea at least 12 consecutive months)

9. Participants must agree to not participate in any other SARS-CoV-2 or influenza
prevention or treatment studies for the duration of the study. Note: For
participants who become hospitalized with COVID-19 or influenza, participation in
investigational treatment studies is permitted.

Exclusion Criteria

If an individual meets any of the following criteria, he or she is ineligible for this
study:

1. History of laboratory-confirmed (by polymerase chain reaction [PCR], rapid antigen
test, or rapid molecular assay) COVID-19, asymptomatic SARS-CoV-2 infection, or
influenza within ≤ 8 weeks prior to Screening.

2. Any ongoing, symptomatic acute illness requiring medical or surgical care or chronic
illness that required substantive changes in medication in the past 2 months prior
to Screening indicating that chronic illness/disease is not stable (at the
discretion of the investigator). This includes any current workup of undiagnosed
illness that could lead to a new condition.

3. Serious chronic diseases inclusive of:

1. Uncontrolled hypertension (NOTE: hypertension ≤ 170/100 is NOT exclusionary);

2. Congestive heart failure requiring hospitalization within 3 months prior to
Screening

3. Chronic obstructive pulmonary disease (COPD) requiring hospitalization within 3
months prior to Screening (NOTE: stable COPD is NOT exclusionary);

4. Within 3 months prior to Screening, evidence of unstable coronary artery
disease as manifested by cardiac interventions (eg, cardiac stent placement,
coronary artery bypass graft surgery), new cardiac medications for control of
symptoms, or unstable angina (NOTE: stable coronary heart disease is NOT
exclusionary);

5. Hospitalization for diabetic ketoacidosis within 6 months prior to Screening

6. Chronic kidney disease/renal requiring institution of substantive new therapy
within 3 months prior to Screening

7. Chronic clinically significant gastrointestinal and hepatic diseases requiring
hospitalization or institution of substantive new therapy within 3 months prior
to Screening. (for example, gastroesophageal reflux disease is NOT
exclusionary)

8. Chronic neurological diseases or neurological compromise preventing access to
the study clinic, compliance with protocol, or accurate reporting of safety.

4. Participation in research involving an investigational product
(drug/biologic/device) within 90 days before planned date of vaccination.

5. Use of COVID-19 prophylactic or treatment monoclonal antibodies or antibody
cocktails within 90 days prior to planned date of vaccination.

6. History of a serious reaction to a prior influenza vaccination or known allergy to
constituents of influenza vaccines - including egg proteins - or polysorbate 80; or
any known allergies to products contained in the investigational product.

7. Any history of anaphylaxis to any prior vaccine.

8. History of Guillain-Barré Syndrome following a previous influenza vaccine.

9. Receipt of any vaccine in the 4 weeks preceding the study vaccination and any
influenza vaccine within 2 months preceding the study vaccination. Note: Routine
vaccinations will not be allowed until after study Day 21 and COVID-19 and influenza
vaccination will not be allowed until after Day 84.

10. Any known or suspected autoimmune or immunosuppressive illness, congenital or
acquired, based on medical history and/or physical examination (NOTE:
well-controlled hypothyroidism and mild psoriasis are not exclusionary).

11. Chronic administration (defined as more than 14 continuous days) of
immunosuppressants or other immune-modifying drugs within 6 months prior to the
administration of the study vaccines. An immunosuppressant dose of glucocorticoid is
defined as a systemic dose ≥ 10 mg of prednisone per day or equivalent. The use of
topical, inhaled, and nasal glucocorticoids is permitted.

12. Administration of immunoglobulins and/or any blood products within the 3 months
preceding the administration of the study vaccine or during the study.

13. Active cancer (malignancy) therapy within 1 year prior to study vaccination (with
the exception of adequately treated non-melanomatous skin carcinoma or lentigo
maligna and uterine cervical carcinoma in situ without evidence of disease, at the
discretion of the investigator).

14. Participants who are breastfeeding, pregnant, or who plan to become pregnant prior
to the EoS.

15. Suspected or known history of alcohol abuse or drug addiction within 2 years prior
to study vaccination, which in the opinion of the investigator, might interfere with
protocol compliance.

16. Acute disease at the time of enrollment (defined as the presence of a moderate or
severe illness with or without fever, or an oral temperature ≥ 38.0°C, on the
planned day of vaccine administration).

17. History of myocarditis or pericarditis.

18. Any condition that in the opinion of the investigator would pose a health risk to
the participant if enrolled or could interfere with evaluation of the vaccine or
interpretation of study results (including neurologic or psychiatric conditions
deemed likely to impair the quality of safety reporting).

19. Study team member or immediate family member of any study team member (inclusive of
Sponsor, Contract Research Organization, and study site personnel involved in the
conduct or planning of the study).

20. Known history of any prior motor neuropathy.