Since the start of the COVID-19, Italy, and particularly the Northern region, Lombardia,has initially been the centre of the most numerous reports of confirmed cases of COVID-19since the spread of the infection to Europe, reaching 5469 cases out of 9172 total casesin Italy (corresponding to 0.054% of the region population) within 2 weeks from theidentification of the first Italian case at the end of February 2020. Data updated at 25March 2020 reported 7503 deaths out of 57521cases in Italy. The overall number ofpatients requiring admission to hospital reached 23112, with another 3489 needingintensive care unit (ICU) management (4). The "Fondazione IRCCS Policlinico San Matteo"Pavia's main teaching and research hospital has become one of the main COVID Centers forthe treatment of the disease. Several departments have been reassigned to the solehospitalization of COVID-19 patients in addition to the Infectious Disease Department andthe Intensive Care (ICU). Moreover, a dedicated emergency room (ER) has been set up.All these measures have given rise to a large amount of clinical, imaging and laboratorydata originating from different sources as well data regarding to type and length of stayin each of the ER, medical departments and ICU, that are of use for diagnostic andprognostic purposes. Also the Fondazione IRCCS Policlinico San Matteo has informationobligations towards the Regional (Regione Lombardia) and National (Istituto Superiore diSanità, ISS) authorities.For these reasons we plan to set up a structured registry to collect these information onour Covid-19 patients using the secured REDCap platform resident on a server of the localInformative Services.