Gabon is the 3rd country most affected by COVID-19 behind Cameroon and DemocraticRepublic of Congo in Central Africa, with 8860 cases and 54 deaths in critically illpatients, since the first confirmed case of COVID-19 on the 10th of March 2020(https://africacdc.org/covid-19/). Most of the individuals infected by SARS-CoV-2 areasymptomatic and they represent a major source of viral spread. To date, Africancountries have been less affected by deaths caused by the Covid-19 pandemic compared toother countries. It is currently unknown why Africa has avoided more deaths and appearsto not simply be due to a lack of testing, since the overall death rate has notincreased. Better quality data on seroprevalence in different African regions and provenexplanations of the differences between Africa and other continents, are urgently needed.The aim of this study is to learn about the proportion of people after a first pic oftransmission, who have been exposed to COVID-19 in Gabon by testing for plasma antibodiesto the SARS-CoV-2 virus.The overall goal of this study is to examine the trend of specific anti-SARS-CoV-2antibodies in Gabonese population.