Official Title
Safety and Effectiveness Study of Low Flow Extracorporeal Membrane Oxygenation(CO2 Removal) Driving by Continuous Hemofiltration Machine the Severe New Corovirus Pneumonia (NCP)
Brief Summary

assess the safety and effectiveness of using low-flow extracorporeal membrane oxygenation(CO2 removal) driving by CVVH machine in the severe NCP patients


Device: Low flow ECMO driving by CVVH machine
With aim to clear CO2 and improve oxygenation, a low flow ECMO treatment(using oxgyenator membrane of kid type ) driving by CVVH machine will be performed in the NCP with severe ARDS
NCP patient with severe ARDS and/or high ventilator supported

Eligibility Criteria

Inclusion Criteria:

- 1. NCP with severe acute respiratory distress syndrome with ratio of partial pressure of arterial oxygen over fraction of inspired oxygen (PaO2:FiO2)10cmH2O

- 2. Driving pressure> 20cmH2O

- 3. RR>30bpm

- 4.PaCO2>55cmH2O and/or PH>7.3

Exclusion Criteria:

- 1. poor venous vascular condition and unavaible for central venous catheter placement

Eligibility Gender
Eligibility Age
Minimum: 14 Years

Yun Long, MD

Yun Long

Yun Long
Principal Investigator
Peking Union Medical College Hospit

Peking Union Medical College Hospital
NCT Number