Official Title
Risk Factors for Severe Disease in Hospitalized Patients With COVID-19 and the Effect
Brief Summary

The purpose of this study is to explore the factors that can affect the development ofsevere cases in hospitalized patients with COVID-19, including basic diseases, laboratoryparameters, and clinical manifestations; In addition,to explore whether Azvudine canreduce the mortality of hospitalized patients with COVID-19.

Detailed Description

4201 COVID-19 patients discharged from our hospital were enrolled. Binary logistic
regression analysis and ROC curve were used to investigate the role of comorbidities,
laboratory parameters and clinical manifestation on progression of COVID-19 patients. We
used propensity-score models conditional on baseline characteristics and Univariate Cox
regression model to examine whether Azvudine can reduce the mortality of COVID-19
patients.

Active, not recruiting
COVID-19

Drug: Azvudine

Received antiviral treatment with azvudine

Eligibility Criteria

Inclusion Criteria:

The COVID-19 positive patients

Exclusion Criteria:

1. patients treated with both azvudine and monotamivir;

2. patients receiving other antiviral drugs such as nematavir/ritonavir;

3. age < 18 years old

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
Countries
China
Locations

The Fifth Affiliated Hospital of Sun Yat-sen University
Zhuhai, Guangdong, China

Not Provided

Fifth Affiliated Hospital, Sun Yat-Sen University
NCT Number
Keywords
Covid-19
Azvudine
Severity
MeSH Terms
COVID-19