Official Title
Real-World Effectiveness and Safety of Oral Azvudine in Hospitalized Patients With COVID-19: A Multicenter, Retrospective, Cohort Study
Brief Summary

To establish a real-world clinical cohort and database of Azvudine in the treatment ofSARS-CoV-2 infection, and to provide stable and reliable evidence for the clinicalefficacy and safety evaluation of azvudine in the treatment of SARS-CoV-2 infection.

Detailed Description

Not Provided

Completed
COVID-19
Azvudine

Drug: Azvudine

Antiviral drug

Drug: Paxlovid

Antiviral drug
Other Name: Nirmatrelvir/Ritonavir

Eligibility Criteria

Inclusion Criteria:

1. Age above 18 years old (including the cut-off value), regardless of gender;

2. Patients diagnosed with 2019-ncov infection according to the diagnostic criteria of
the latest edition of the Diagnosis and Treatment Plan for 2019-ncov Pneumonia
issued by the Health Commission of China;

3. Informed consent has been signed.

Exclusion Criteria:

1. Known or suspected allergic to the components of Azivudine tablets;

2. Patients with severe liver, kidney, heart and other organ damage;

3. Pregnant or lactating women who planned to give birth during or within 6 months
after the trial;

4. Had participated in other clinical trials or were using investigational drugs within
12 weeks before medication;

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
Countries
China
Locations

The First Affiliated Hospital of Zhengzhou University
Zhengzhou 1784658, Henan 1808520, China

Zujiang Yu, Dr., Study Director
The First Affiliated Hospital of Zhengzhou University

The First Affiliated Hospital of Zhengzhou University
NCT Number
MeSH Terms
COVID-19
azvudine
Nirmatrelvir and ritonavir drug combination