The goal of this clinical trial is to test if a Lingzhi supplement (CP003) helps peoplewith chronic fatigue or post-COVID fatigue feel better. It will also check if thesupplement is safe to use. The main questions it aims to answer are:Does the Lingzhi supplement reduce fatigue symptoms? Is it safe to take? How does itaffect the body's immune system and inflammation?Researchers will compare people taking the Lingzhi supplement to those who don't takeanything (waitlist group) to see if it works.Participants will: - Take 5 capsules once daily for 6 weeks (or wait to start treatment if in waitlist group) - Visit the clinic 2 times for blood tests (before and after taking the supplement) - Complete questionnaires 3 times about their fatigue and quality of life (4 times questionnaires for waitlist group)
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Drug: LingZhi capsule
Lingzhi-containg capsules (CP003) is a Chinese Medicine nutritional supplement
manufactured by Chinese Pharm CO LTD containing: wild red ganoderma extract, ganoderma
spore powder (99.9% broken wall), β-nicotinamide mononucleotide (NMN), wild yellow
ganoderma extract, wild green ganoderma extract, wild purple ganoderma extract, wild
white ganoderma extract, wild black sesame extract
Inclusion Criteria:
- Meet the Fukuda diagnostic definition of CFS/ME or have persisting fatigue after the
infection of SARS-CoV-2
- Are able to complete a 6-week course of intervention;
- Able to complete the online validated fatigue surveys.
Exclusion Criteria:
- Have participated in any type of complements or herbal medicine within the past six
months;
- Have serious medical conditions that might limit their participation in this
intervention;
- Diagnosed with acute inflammation;
- Are pregnant or are planning a pregnancy in the next 3 months.
Specialist Clinical Centre for Teaching and Research, School of Chinese Medicine, The University of Hong Kong
Hong Kong, Hong Kong
Investigator: TUNG LEONG FONG
Contact: +852 5660 4020
tlfong@hku.hk
TUNG LEONG FONG
+852 5660 4020
tlfong@hku.hk
Guang Chen
+852 3917 6515
gchen91@hku.hk
Not Provided