Implementing WGS, it is advisable to involve a variety of relevant actors and to consider
the opinions of various stakeholders, including those who are not professionals in the
field. This might resolve the implementation problem that could occur if psychological
and social dimensions or, in other words, not strictly scientific criteria are not
adequately integrated in decision making concerning complex issues such as innovations in
genetics. In most cases, the reaction towards genetic information corresponds with a
specific personal view of how to handle medical information and thus amplifies already
existing mental phenomena (fear, stress, worries, etc.), tendencies of self-improvement
and self-care and curiosity and playfulness.38 In the Study from Lewis et al,
investigated in this relation the specific personality traits of participants of the
first implementations of WGS, who were characterized as optimistic and resilient. This is
a phenomenon often found in the group of early adopters of new technologies in general as
described in the dimension knowing as empowerment to act, for some people, the
willingness to know is caused by an attitude of openness towards the unknown and the
desire to open new scenarios that could activate new opportunities for research as well
as for themselves. This perspective highly reflects the currently dominant societal goal
of health prevention and the main health policy discourse and practice of precaution.
People have different perceptions of WGS and its imaginable integration into our health
care system or our daily lives, and various approaches to decision-making regarding the
potential use of WGS could be observed.

There are suboptimal national resources, inadequate specimen sampling strategies, to
optimize epidemiological and clinical inference. There is a gap in the meta-data to
interpret SC2-WGS information and other genomic sequencing (Gut microbiome, Genome Wide
Sequencing for Prenatal Detection, Tuberculosis Metagenomic sequencing, Nutrigenetics and
Cancer Next Generation Sequencing) in a complete and rapid manner. This understanding gap
can undermine broad-scale government and public support as a routine part of the pandemic
response, especially in low- and middle-income countries.

Therefore an intervention is needed in the form of genomic sequencing education. Before
the intervention stage, there will be taking survey data which will be collected using
the themes from the FGD results and will focus on assessing public perceptions regarding
SC2-WGS and other genomic sequencing. These themes will be formulated into short
statements and answered by respondents using a Likert scale. The survey will involve
100-200 respondents via WhatsApp chat bot. Subjects will be asked to express their
reactions to short statements on a 4-point Likert scale. The subject will also be asked
to express his emotional reaction to the statement with a series of binary questions
related to positive or negative feelings. The survey results will be analyzed
quantitatively to see the total score and distribution of each statement.

The next stage in this research is to develop social media and communication media. At
this stage we will formulate public messages and strategies to improve perceptions based
on the survey results. The public message formulated will be useful for educating the
public using various social media platforms.

The intervention stage will be carried out by distributing information regarding genome
sequencing via bots. After the intervention is carried out, changes in perception will be
assessed before and after the intervention through pre-test and post-test questionnaires