The goal of this randomized controlled double-blind parallel-group interventional trialis to evaluate the effects of of dietary supplementation with a pre-probiotic on patient-and clinician-reported outcomes, and brain tissue metabolism in patients with post-covidfatigue syndrome.
Not Provided
Dietary Supplement: Dietary Supplement: Experimental
Combination of pre-probiotic
Dietary Supplement: Dietary Supplement: Placebo
Inert compound
Inclusion Criteria:
- Age 18 - 65 years
- Covid-19 positive test within last 3 months (as documented byvalid PCR or
antigentest
- Moderate-to-severe fatigue (20-MFI test total score > 43.5)
- At least one of additional covid-19 related symptoms
(anosmia,ageusia,breathingdifficulties,lungpain, body aches, headaches, difficulties
concentrating etc.)
Exclusion Criteria:
- Other pulmonary and cardiovascular conditions
- History of dietary supplement use during the past 4 weeks
- Organic gastrointestinal (GI) disorders such as inflammatory bowel disease, coeliac
disease, eosinophilic disorders, or current infection of the GI tract.
- Bowel surgery or short bowel syndrome.
- Medication or supplement which can impact the gut microbiome, including:
antibiotics, antimicrobials, or antifungals in the two months
- Probiotic or prebiotic supplements in the last 4 weeks
Applied Bioenergetics Lab at Faculty of Sport and PE
Novi Sad 3194360, Vojvodina 784272, Serbia
Not Provided