Official Title
Post COVID-19 Biorepository
Brief Summary

Establish a biorepository, clinical data registry, and radiographic image database fromindividuals who were COVID positive at one time and are being seen for outpatientfollow-up or a separate study visit.

Detailed Description

Living patients or their healthcare surrogates will provide informed consent prior to
participation in the biorepository. Surrogate decision makers who cannot consent in
person will be consented in accordance to the KUMC remote consent guidelines.
Biospecimens to be collected include serum, plasma and whole blood. Blood samples will be
collected during face-to-face encounters in the Post-COVID-19 clinic within the TUKHS
pulmonary clinic or will be coordinated with other outpatient follow-up appointments
(including separate procedure/lab-related visits) or separate study visits for ongoing,
indepent studies. Samples will be collected at time of consent as well as at potential
follow-up visits at approximately 3, 6, 12, and 12 months from enrollment. Blood samples
will be processed, aliquoted, and stored at -80°C. A portion of the blood samples will be
kept for DNA and RNA isolation, and a portion of plasma collected might be utilized to
isolate peripheral blood mononuclear cells. Biospecimens will be labeled with the
patient's study ID number, date of sample processing, and specimen type. Biospecimens
will be stored through the duration of the study. If the patient chooses to withdraw
consent, his or her samples in the biorepository will be destroyed. Biospecimens that
have been previously used or disseminated will continue to be utilized. Future research
may include whole genome testing, and these results will not be shared with the patient
or their standard of care physician.

Patient data and historical radiographic imaging from after the date of consent will be
collected using TUKHS medical records and stored in RedCap. The data to be collected is
outlined in the data collection sheets.

Recruiting
Coronavirus Infection
Eligibility Criteria

Inclusion Criteria:

1. The participant is a patient at TUKHS or has agreed to participate in a study
approved by the KUMC Human Research Protection Program (HRPP).

2. The participant has a previous diagnosis of COVID-19 confirmed by COVID-19 PCR or
antibody testing and is being seen for outpatient follow-up.

3. Patient is ≥ 18 years of age or older.

Exclusion Criteria:

1. Participant declines to participate.

2. Participant or healthcare surrogate is unable to provide informed consent.

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
Countries
United States
Locations

University of Kansas Medical Center
Kansas City, Kansas, United States

Investigator: Adam M Ruff, BS
Contact: 913-574-3932
aruff@kumc.edu

Investigator: Leslie A Spikes, MD

Contacts

Adam M Ruff, BS
9135743932
aruff@kumc.edu

Luigi R Boccardi, MPH
9135884022
lboccardi@kumc.edu

University of Kansas Medical Center
NCT Number
MeSH Terms
Coronavirus Infections