Inclusion Criteria:

1. Healthy male or female subjects aged ≥18 years of age;

2. Subjects who are in good physical condition as judged by the investigator based on
medical history, physical examination and clinical laboratory tests;

3. Subjects who have not been previously vaccinated with a Covid-19 vaccine or who have
received the last dose (total dose ≤ 3 doses) of a Covid-19 vaccine at least 6
months ago;

4. Subjects who have not been previously infected with Covid-19, or whose nucleic acid
or antigen test has turned negative for more than 3 months after previous Covid-19
infection;

5. Subjects are able to understand the study procedures, have provide written informed
consent, and are able to comply with the requirements of the clinical study
protocol.

Exclusion criteria

1. Axillary temperature ≥37.3°C;

2. Positive polymerase chain reaction (PCR) test results within the last 48 hours;

3. Women of childbearing potential with a positive urine pregnancy test result, or who
are pregnant or breastfeeding, or who have not used effective contraception within 2
weeks prior to enrolment, or women and men who plan to have children within 12
months after full immunisation;

4. History of epilepsy, convulsions or seizures, psychosis or family history of
psychosis;

5. Have a history of severe allergy to any medication or vaccination (e.g. acute
allergic reaction, urticaria, skin eczema, dyspnoea, angioneurotic oedema, or
abdominal pain) or allergy to known components of a Covid-19 vaccine;

6. Have a history of hospital-diagnosed thrombocytopenia or other coagulation
disorders;

7. Have a history of hospital-diagnosed known immunological impairment or hypofunction;

8. Subjects who have received whole blood, plasma or immunoglobulin therapy within 3
months;

9. Known or suspected concomitant serious diseases, including: respiratory diseases,
acute infections or active chronic diseases, liver and kidney diseases, severe
diabetes, malignant tumours, infectious or allergic skin diseases, and HIV infection
(with test report);

10. Have serious cardiovascular diseases, cardiopulmonary failure, hypertension that
cannot be controlled by medication (systolic blood pressure ≥ 140mmHg and/or
diastolic blood pressure ≥ 90mmHg on physical examination);

11. Received live attenuated vaccine within 1 month prior to vaccination or other
vaccines within 14 days prior to vaccination;

12. Participation in a clinical trial of another drug within 3 months prior to the first
dose of vaccine or planning to participate in a clinical trial of another drug
during the study period;

13. Any other conditions that the investigator considers inappropriate for participation
in this study.