The primary aim is to study the short-term outcome of elderly ICU patients (≥ 70 years)suffering from COVID-19 using a multicenter and multi-national approach. The secondaryaim is to investigate the properties of a simple frailty scale in this cohort, and inparticular if this is an instrument that can be used for outcome prediction in thisgroup. In addition, various other parameters of potential relevance for older criticallyill patients will be studied.
The study started in March 2020 and included until summer 2021 nearly 4000 patients.
Several comprehensive analyses were conducted and published. Subsequently, in December
2021 the protocol was slightly changed and recruitment continues in 2022.
Data are collected regarding: Pre-Admission life conditions with Frailty (Clinical
Frailty Scale, CFSF.R.A.I.L Score); vaccination status; ICU-Admission (e.g. SOFA),
ICU-Treatment, Survival (30 day and 3 months).
Data are collected electronically through an e-CRF and with baseline documentation of the
ICU. The database is located in Denmark, at the Department of Epidemiology, University of
Aarhus. Each ICU will only have access through the database of their own patients, and
patient ID is not registered (Names, birth-date or social security numbers) so it is in
that sense anonymous.
The goal is to recruit at up to 400 ICUs that will continuously collect data. The COVIP
Study had two different previous recruitment periods. Period 1 (march to May 2020)
finished representing the first wave of the pandemic in most countries. The second
recruitment period has been defined being from September 1st to December 31st 2020
representing the second wave in most countries. Recruitment in 2021 also continued until
the summer without allocating a specific recruitment period. However, the third
recruitment period opened January 1st 2022 and is still ongoing.
Inclusion Criteria:
1. Age > 70 years
2. ICU-Admission
3. Infection with SARS-CoV-2
Exclusion Criteria:
1. Age <70 years
Department of Intensive Care, Aarhus University Hospital
Aarhus, Denmark
Hôpitaux de Paris, Hôpital Saint-Antoine, service de réanimation médicale
Paris, France
INSERM, UMR_S 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique
Paris, France
Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique
Paris, France
Division of Cardiology, Pulmonary Disease and Vascular Medicine
Duesseldorf, Germany
Department of Anaestesia and Intensive Care, Haukeland University Hospital
Bergen, Norway
Department of Clinical Medecine,University of Bergen
Bergen, Norway
Christian Jung, MD
+2118118800
contact@vipstudy.org
Raphael Bruno, MD
+2118118800
covip@med.uni-duesseldorf.de