The goal of this observational study is to learn about sarcoidosis development afterCOVID-19 infection.The main question it aims to answer is: - prevalence of Sarcoidosis among patients previously infected with COVID-19.Participants will: - provide previous positive RT-PCR for COVID-19 - Have computed tomography of the Chest with suggestive findings of sarcoidosis - Have bronchoscopic guided biopsies and pathological analysis to detect number of patients with sarcoidosis.
This prospective cross sectional study was performed on a total of 55 patients with
mediastinal and /or hilar lymphadenopathy with or without lung infiltrates referred to
Bronchoscopy unit , Chest department, Ain-Shams University hospital for biopsy taking and
diagnosis.
All patients were subjected to the following : history taking , clinical examination ,
radiological assessment by computed tomography (CT )chest , fiberoptic bronchoscopy where
biopsies were taken either by conventional-Trans-bronchial needle aspiration (c-TBNA) ,
endo-bronchial ultrasound (EBUS-TBNA) or direct forceps biopsies and sent for
histopathological examination and if the patient had past history of COVID-19 infection
with previous positive reverse transcriptase- polymerase chain reaction assay (RT-PCR).
Procedure: flexible bronchoscopy
fiberoptic bronchoscopy was done where biopsies were taken either by conventional TBNA
(c-TBNA) , EBUS-TBNA or direct forceps biopsies and sent for histopathological
examination
Inclusion Criteria:
- All adult patients with previous positive RT-PCR for COVID -19 and CT chest findings
of mediastinal and or hilar lymphadenopathy with or without lung infiltrate will be
included. .
Exclusion Criteria:
- Patients younger than 18 years old Patients
- Patients refuse to participate in the study
- Patients previously diagnosed as sarcoidosis
Hoda atiatullah
Cairo 360630, Egypt
Hoda A Mohamed, MD, Principal Investigator
faculty of medicine, Ain Shams university