Official Title
A Double-blind, Randomized Study to Evaluate the Efficacy and Safety of Bezisterim (NE3107) in Adults With Long COVID
Brief Summary

Long COVID is a condition where debilitating symptoms can persist for months after aCOVID-19 infection. This study aims to evaluate the effects of NE3107 on severalneurological symptoms reported in people with Long COVID including difficultyconcentrating or remembering things ("brain fog") and fatigue.Researchers will compare NE3107 to a placebo (a look-alike substance that contains nodrug) to see if NE3107 works to treat neurocognitive and fatigue symptoms of long COVID.Participants will: - Take NE3107 or a placebo twice daily for 84 days - Visit the clinic 5 times for checkups and tests and have a follow up phone call

Detailed Description

Not Provided

Recruiting
Long Covid

Drug: NE3107

20 mg Capsule
Other Name: bezisterim

Drug: Placebo

placebo capsule

Eligibility Criteria

Inclusion Criteria:

- 18 years to 64 years of age

- diagnosed with Long COVID with symptoms of fatigue and brain fog for at least 3
months

- agree to use birth control measures

- provide voluntary consent

- willing to allow blood collection

- pass all screening tests and procedures

Exclusion Criteria:

- has received a COVID-19 vaccination within 30 days

- previous admission to the intensive care unit for COVID-19

- medical history of major mental or physical illness prior to COVID-19 infection

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: 64 Years
Countries
United States
Locations

Clinical Trial Site
San Francisco, California, United States

Clinical Trial Site
Jacksonville, Florida, United States

Clinical Trial Site
Silver Spring, Maryland, United States

Clinical Trial Site
Farmington Hills, Michigan, United States

Contacts

Penelope Markham, PhD
pmarkham@bioviepharma.com

Not Provided

NCT Number
Keywords
Covid-19
Neurocognition
Fatigue
Post-exertional malaise
Sleep
SARS-CoV-2
brain fog
MeSH Terms
Post-Acute COVID-19 Syndrome