Vascular modifications have been described during SARS-CoV2 infection, especially adilatation of the bronchial arteries. Within the airway wall, small branches of thebronchial arteries cross the muscle layer to develop a submucosal network. The NarrowBand Imaging technique is used during bronchoscopy to achieve a maximum contrast ofvessels and the surrounding mucosa. Therefore, it enables to observe the microvesselstructure and its distribution in the bronchial mucosa. The aim of this study is todescribe the vasculature pattern of the bronchial tree during infection with SARS-CoV2.
Not Provided
Other: NBI images and/or videos
A library of NBI images and/or videos will be established from previously recorded
bronchoscopies in 30 patients (10 with a SARS-CoV2 infection, 10 with a lower respiratory
tract infection not related to SARS-CoV2, and 10 in patients with pulmonary nodule). NBI
images and/or videos of the bronchial tree will then be analysed by three experimented
interventional pulmonologists blinded to the patient ID. Each investigator will describe
the vasculature pattern according to a prespecified grid: Normal mucosal vascularity /
increased capillary density / presence of capillary loops / presence of dotted vessels /
complex vascular networks of tortuous vessels or abrupt ending vessels / dilated
longitudinal vessels. In case of discordance between the investigators, images will be
reviewed to obtain a consensus.
Inclusion Criteria:
- Patients who undergo bronchoscopy with image and/or videos recording of NBI aspect
of the proximal bronchial tree (carina, right and left upper lobe).
- Patients hospitalized with SARS-CoV2 infection proven by RT-PCR test
- patients hospitalized with lower respiratory tract infections unrelated to SARS-CoV2
(RT-PCR negative for SARS-CoV2)
- Patients who have had bronchoscopy performed as part of the assessment of a distal
pulmonary nodule (RT-PCR negative for SARS-CoV2).
Exclusion Criteria:
- Patients under legal protection
- Patients who refuses the use of his personal medical data
CHU Amiens
Amiens, France
Not Provided