Official Title
A Multi-Site Clinical Evaluation of the LIAISON NES FLU A/B, RSV & COVID-19 Assay in Symptomatic Patients
Brief Summary

The DiaSorin Molecular LIAISON® NES FLU A/B, RSV & COVID-19 real-time polymerase chainreaction (RT-PCR) assay is intended for use on the DiaSorin LIAISON® NES instrument forthe in-vitro qualitative detection and differentiation of nucleic acid from influenza A,influenza B, RSV and SARS-CoV-2 virus from dry nasal swabs (NS) from human patients withsigns and symptoms during the acute phase of respiratory tract infection in conjunctionwith clinical and epidemiological risk factors.The LIAISON® NES FLU A/B, RSV & COVID-19 assay is intended for use as an aid in thedifferential diagnosis of influenza A, influenza B, RSV and SARS-CoV-2 infection in aprofessional laboratory setting.Negative results do not preclude influenza A, influenza B, RSV or SARS-CoV-2, infectionand should not be used as the sole basis for patient management decisions. The assay isnot intended to detect the presence of the influenza C virus.

Detailed Description

Not Provided

Recruiting
Influenza A
Influenza B
RSV
COVID 19

Diagnostic Test: LIAISON NES FLU A/B, RSV & COVID-19

The LIAISON® NES FLU A/B, RSV & COVID-19 assay used on the LIAISON® NES instrument is a
real-time PCR system that enables the direct amplification, detection and differentiation
of Flu A viral RNA, Flu B viral RNA RSV viral RNA, and SARS-CoV-2 RNA from dry nasal
swabs. Nasal Swabs can be professionally collected by a Healthcare Provider or
self-collected by the patient under the supervision of the healthcare provider. The
collected nasal swab can then be directly loaded into the cartridge without nucleic acid
extraction.

Eligibility Criteria

Inclusion Criteria:

- The specimen is a NPS or NS from a patient collected and preserved in 3 mL Universal
Transport Media (UTM), BD Universal Viral Transport (UVT), or MicroTest M4RT
transport media, or 1 mL Copan Eswab (Liquid Amies).

- The specimen is from a patient who is either hospitalized, admitted to a hospital
emergency department, visiting an outpatient clinic or resident of a long-term care
facility.

- The specimen is from a human patient with active signs and symptoms of respiratory
tract infection at time of collection

- Specimen stored at 2-8°C for up to 72 hours from collection. If there is a delay in
testing, store specimen at ≤-70 °C.

- The total volume of the leftover specimen received is ≥1.5 mL, except for specimens
collected in Liquid Amies which requires a total leftover volume of ≥0.5 mL

- The specimen was received in good condition (no leakage or drying of the specimen).

Exclusion Criteria:

- Incorrect swab type

- Incorrect transport media

- Incorrect specimen handling (e.g. specimens not stored at recommended temperature)

- The specimen has undergone more than two freeze/thaw cycles

- Specimens collected with calcium alginate or organic swabs

Eligibility Gender
All
Eligibility Age
Minimum: N/A ~ Maximum: N/A
Countries
United States
Locations

PAS Research - Henderson
Henderson, Nevada, United States

PAS Research - Pittsburgh
Pittsburgh, Pennsylvania, United States

PAS Research - McAllen
McAllen, Texas, United States

Contacts

Janet Farhang
5124015472
janet.farhang@diasorin.com

Not Provided

DiaSorin Molecular LLC
NCT Number
MeSH Terms
COVID-19
Influenza, Human