Official Title
Levels of Physical Activity After SARS-CoV-2 Infection in Greek Adults: the Role of Pre-illness Vaccination and the Number of Reinfections.
Brief Summary

Coronavirus infection has an impact on several aspects of everyday life including thelevels of Physical Activity (PA). Investigators wish to (1) detect changes on PA levelsin recovered SARS-CoV-2 (COVID-19) adults compared to the pre-infection levels and (2)identify a potential relationship between changes of PA levels and pre-illnessvaccination profile along with individual's number of infection/reinfections. It isassumed that the impact of COVID-19 infection on PA would be more pronounced in cases ofrepeated infections and/or in the unvaccinated compared to the vaccinated individualsagainst COVID-19.

Detailed Description

Coronavirus identified in 2019, SARS-CoV-2 (COVID-19), has caused a pandemic of
respiratory illness in which manifestation ranging from asymptomatic presentation to
critically illness with severe pneumonia, acute respiratory distress syndrome,
respiratory failure, or multiple organ failure. It may influence several aspects of
everyday life including the levels of Physical Activity such as walking, cycling, sports
or active recreation and, thus, has negative effect on general health and quality of
life. Recent findings demonstrate a relation between COVID-19 infection and impairment in
functional capacity, and suggest that may also be associated with an increased risk of
acute and post-acute death. Moreover, individuals who have been infected might suffer
long-term consequences as a result of their infection (Long COVID), for few weeks (short
term) or 10-20 weeks (medium term) or more than six months (long term) post-infection.

The current study is designed to assess changes in PA (overall and in four domains i.e.
daily occupation, transportation to and from daily occupation, leisure time activities,
and regular sporting activities) caused by COVID-19 infection (i.e. in the short term, 4
weeks post infection) concerning the pre-illness vaccination profile and the number of
infections/reinfections using a web-based validated questionnaire in a large population
of Greece. Investigators hypothesize that the impact of COVID-19 infection on PA levels
would be more pronounced in cases of repeated infections and/or in the unvaccinated
compared to the vaccinated individuals against COVID-19. With regard to the potential
burden of COVID-19 in functional capacity, investigators wish:

1. to detect changes on PA levels in recovered COVID-19 adults compared to the
pre-infection levels as a result of a post-effect impact;

2. to identify a potential relationship between changes of PA levels and pre-illness
vaccination profile along with individual's number of infection/reinfections so as
to detect correlations amongst different parameters.

The Greek version of the revised Active-Q (AQGR) which is a self-reported, online,
interactive physical activity questionnaire that assesses adult's habitual activity on
weekly basis (in four main PA domains: daily occupation, transportation to and from daily
occupation, leisure time activities, and regular sporting activities) is employed.
Regarding questions of medical treatment during COVID-19 infection, individual's number
of infection/reinfections and other relative parameters, additional questionnaire items
have been incorporated. In total, the current web-based questionnaire consisted of 60-67
questions, based on previous responses and follow-up patterns, and will be extensively
used to address the aims of the current study.

Recruiting
COVID-19 (Coronavirus Disease 2019)
Eligibility Criteria

Inclusion Criteria:

COVID-19 recovered individuals aged from 18 to 80 years old.

Exclusion Criteria:

Individuals without any confirmed COVID-19 infection, severe musculoskeletal problems,
cognitive impairment/dementia, participation in any strict weight loss control program,
gestation or childbirth within one year of the study's start date.

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: 80 Years
Countries
Greece
Locations

National and Kapodistrian University of Athens
Athens, Attica, Greece

Investigator: Emmanuil D. Zacharakis, PhD
emzach@phed.uoa.gr

Contacts

Emmanouil D. Zacharakis, PhD
(+30)
emzach@phed.uoa.gr

Panteleimon Bakirtzoglou, PhD
(+30) 6972207967
bakirtzoglou@phed.auth.gr

Emmanouil D. Zacharakis, PhD, Principal Investigator
National and Kapodistrian University of Athens

Emmanouil D. Zacharakis
NCT Number
Keywords
Physical Activity, exercise, public health, Post COVID
MeSH Terms
COVID-19