Official Title
Intensive Attention Training to Treat Brain Fog in Individuals With Long-Covid
Brief Summary

This study is to find out if the Attention Processing Training program is a potentialtreatment for brain fog symptoms, reported by people with Long-Covid. Also investigatingthe feasibility of completing this program virtually.

Detailed Description

The goal of this project is to test the feasibility, acceptability and efficacy of an
attention training intervention (Attention Process Training; APT-3) as a potential
treatment for brain fog symptoms experienced by people with Long-Covid. There already is
good empirical evidence to support the idea that the APT-3 treatment is feasible and
effective in improving attention in people with acquired brain injuries, but information
about its efficacy and acceptability in people with Long-Covid brain fog is lacking.

Recruiting
Long Covid

Other: Attention Training

The APT-3 is an evidence-based, standardized computer-based training program that was
designed to improve attention skills that underlie higher level cognitive processes
(e.g., executive functions and memory).
Other Name: APT-3

Other: Music Group

This group will listen to a pre-determined playlist of music following the same dosing as
the attention training group as stated in the arms.

Eligibility Criteria

Inclusion Criteria:

- Aged 18-65 years. Live in the Chicagoland area

- A history of confirmed SARS-CoV-2 infection.

- Subjective reports of cognitive symptoms that interfere with everyday activities,
starting on or shortly after SARS-CoV-2 infection.

- Continuation or development of Long-Covid brain fog 3 months after the initial
SARS-CoV-2 infection, with these symptoms lasting for at least 2 months with no
other explanation.

- Objective attentional deficits as measured by the Conners CPT-312, and/or the Digit
Span subtest (WAIS- III13).

- Able to use a keyboard.

- Able to understand and communicate in English.

- Able to consent independently.

Exclusion Criteria:

- Being hospitalized due to COVID-19 diagnosis for more than 3 days.

- Pre-morbid neurological conditions that could potentially affect cognition, such as
Parkinson's Disease, Alzheimer's Dementia, acquired brain injury.

- Severe depression.

- Currently enrolled in cognitive training or physical exercise training.

- Receiving chemotherapy or radiation within last 6 months.

- Active substance abuse.

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: 75 Years
Countries
United States
Locations

Shirley Ryan AbilityLab
Chicago 4887398, Illinois 4896861, United States

Investigator: Kathryn L Magee
Contact: 312-238-6451
Longcovid@sralab.org

Contacts

Kathryn Magee, MHS
(312)238-6451
LongCovid@sralab.org

Shirley Ryan AbilityLab
NCT Number
Keywords
Covid-19
brain fog
MeSH Terms
Post-Acute COVID-19 Syndrome
COVID-19
Mental Fatigue