This prospective observational study aims to investigate the impact of transcatheteraortic valve implantation (TAVI) and transcatheter mitral valve edge-to-edge repair(M-TEER) on sleep-disordered breathing (SDB) in patients with significant valvular heartdisease. Patients undergoing TAVI or M-TEER will be evaluated with full polysomnographyprior to the intervention and at 6 months follow-up. Changes in sleep parameters,including apnea-hypopnea index (AHI), central and obstructive apnea indices, oxygendesaturation, and sleep architecture, will be assessed. In addition, the study willexplore the association between changes in SDB and echocardiographic as well asarrhythmic parameters. The findings are expected to improve the understanding of theinteraction between valvular heart disease and SDB and to identify potential benefits oftranscatheter interventions on sleep-related outcomes.
Not Provided
Inclusion Criteria:
- Adult patients undergoing TAVI or M-TEER
- Ability to undergo polysomnography
- Provision of written informed consent
Exclusion Criteria:
- Inability to undergo sleep study (polysomnography)
- Inability to complete follow-up at 6 months
- Cognitive impairment (e.g., dementia)
- Refusal to participate
Hippocratio General Hospital of Athens
Athens, Attica, Greece
Investigator: Aristides Plaitis, MD, MSc
Contact: +306945023017
aris.plaitis@gmail.com
Aristides Plaitis, MD, MSc
+306945023017
aris.plaitis@gmail.com
Not Provided