Official Title
EFFECTS OF WHEY PROTEIN SUPPLEMENTATION ON CARDIOPULMONARY, MUSCLE AND IMMUNOHEMATOLOGICAL RESPONSES OF POST-COVID-19 PATIENTS.
Brief Summary

Background: COVID-19 left consequences in different organs from months to years requiringdifferent types of rehabilitation. In fact, a severe loss in the lung function, and inthe respiratory and peripheral muscle strength is commonly observed in post-COVID-19patients. Objectives: Thus, the present study investigated whether 30 days ofsupplementation with a nutritional blend (ImmuneRecov®; composition: whey proteinconcentrate, astaxanthin, creatine, selenium, vitamin C, glutamic acid, tryptophan,magnesium) would help to minimize the respiratory (lung function) and muscular(respiratory and peripheral muscles) sequelae in post-COVID-19 patients.

Detailed Description

Background: COVID-19 left consequences in different organs from months to years requiring
different types of rehabilitation. In fact, a severe loss in the lung function, and in
the respiratory and peripheral muscle strength is commonly observed in post-COVID-19
patients. Objectives: Thus, the present study investigated whether 30 days of
supplementation with a nutritional blend (ImmuneRecov®; composition: whey protein
concentrate, astaxanthin, creatine, selenium, vitamin C, glutamic acid, tryptophan,
magnesium) would help to minimize the respiratory (lung function) and muscular
(respiratory and peripheral muscles) sequelae in post-COVID-19 patients. Design: This is
a non-controlled open label prospective clinical study. Methods: Fifty-eight
post-COVID-19 patients were recruited and twenty-four accepted to take the nutritional
blend, while twenty-four did not accept but required to participate in the evaluations
and 10 refused to participate. So, the patients were evaluated before the 14th day after
hospital discharge and after 30 days of use of the nutritional blend or control (no
supplementation).

Recruiting
Long Covid19
Dietary Supplements
Respiratory Tract Infections
Inflammation

Dietary Supplement: Nutritional blend (ImmuneRecov).

Effects of 30 days supplementation with ImmuneRecov on Peripheral and Respiratory Muscle
Strength, on Lung Function and Immune Response.

Eligibility Criteria

Inclusion Criteria: The inclusion criteria encompassed post-COVID-19 patients with a
confirmed COVID-19 diagnosis through a positive RT-PCR test, who also required
hospitalization, meeting the criteria for moderate severity classification as defined by
the World Health Organization (WHO). In summary, according to the WHO, moderate illness
is characterized by individuals who exhibit signs of lower respiratory disease during
clinical assessment or imaging and maintain an oxygen saturation level (SpO2) of ≥94%
while breathing room air at sea level.

Exclusion Criteria: Exclusion criteria included individuals discharged from the hospital
for more than 14 days and those who initiated physical activity or began taking any
dietary supplements or vitamins.

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
Countries
Brazil
Locations

Laboratory of Pulmonary and Exercise Immunology
Sao Jose dos Campos, Sao Paulo, Brazil

Laboratory of Pulmonary and Exercise Immunology - Federal University of Sao Paulo
São José dos Campos, SP, Brazil

Contacts

Rodolfo de Paula Vieira, BSc., MSc., PhD.
55 12 991410615
rodrelena@yahoo.com.br

Rodolfo de Paula Vieira, BSc., MSc., PhD., Principal Investigator
Federal University of São Paulo

Federal University of São Paulo
NCT Number
Keywords
Covid-19
dietary supplementation
inflammation
LUNG FUNCTION
muscle strength
SARS-CoV-2
MeSH Terms
COVID-19
Respiratory Tract Infections
Inflammation