Official Title
Hyperbaric Oxygen Therapy (HBOT) as a Treatment for COVID-19 (COVID-19) Infection
Brief Summary

Patients who meet inclusion criteria will be randomized into treatment vs control group. Treatment groups will undergo Hyperbaric Oxygen Therapy (HBOT) and compared to the control group.

Detailed Description

After enrollment, patients will be randomized into treatment vs control group. Both
populations will receive the same inpatient medical treatment. All patients in the treatment
group will undergo hyperbaric oxygen therapy under the same treatment protocol. After
completion of the treatment protocol, specific study endpoints will be compared between the
treatment and control groups.


Device: Hyperbaric Oxygen Therapy

Hyperbaric Oxygen Therapy delivered at a specific uniformed pressure and duration.

Eligibility Criteria

Inclusion Criteria:

- Adult inpatients >18 years old

- Positive PCR COVID-19 testing

- CT evidence of interstitial opacity

- Oxygen saturation <90% on room air

- pO2 = 55-70.

Exclusion Criteria:

- Increased oxygen requirements

- Hemodynamic instability (MAP<65)

- Bradycardia (HR<50)

- History of seizure disorder

- Pneumothorax

- GFR<30

- Hemodialysis

- Refractory anxiety/claustrophobia

- Current pregnancy

- Uncorrectable hypoglycemia

Eligibility Gender
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
United States

Ochsner Medical Center
New Orleans, Louisiana, United States

Jeffery S Kuo, MD, Study Chair
Ochsner Health System

Ochsner Health System
NCT Number
MeSH Terms