Official Title
Home Blood Pressure Self-Management in Hypertensive Stroke Survivors: a Pilot Study
Brief Summary

The purpose of this pilot study is to assess the feasibility of implementing a home blood pressure self-management program in a population of recent stroke survivors in the Washington, D.C. area. The investigators hypothesize that hypertensive stroke survivors in the Washington, DC area who participate in the Home Blood Pressure Monitoring program will have a greater reduction in mean systolic blood pressure (SBP) from baseline to 3 months, as measured by automated office blood pressure (AOBP), as compared to usual care.

Detailed Description

The purpose of this trial is to determine if a home blood pressure self-management (HBPS)
program, including home monitoring and medication adjustments, is practical to use in recent
stroke survivors and whether or not it is associated with lowering blood pressure after 3
months. Data from this trial may be used to do more research and may be used by doctors when
seeing patients.This research is being done because high blood pressure, also called
hypertension, is the leading risk factor for stroke. Lowering blood pressure (BP) has been
shown to lower the risk of future strokes. The majority of stroke survivors continue to have
uncontrolled BP. Currently, blood pressure (BP) is most often measured in the doctor's
office. However, those single BP measurements are not the best picture of blood pressure over
time and can be influenced by the stress of being in a doctor's office, known as the "white
coat effect". This is why measuring BP at home may paint a more accurate picture of a
patient's true long-term BP. Home blood pressure monitoring (HBPM) is recommended in the
recently updated national hypertension guidelines. Home BP monitoring plus guided BP
medication self-adjustments is associated with lower BP in patients with high blood pressure.
The investigators believe that a HBPS program, including medication self-adjustment and home
monitoring, may help to reduce blood pressure in patients with hypertension within 3 months.

Unknown status
Ischemic Stroke

Device: Home Blood Pressure Monitoring Device (Qardio Arm)

The Home Blood Pressure Device with telemonitoring capability will allow the participants and physician to monitor blood pressure over time and titrate blood pressure medications as needed for persistently elevated blood pressure.
Other Name: Medication Self-Titration

Other: Primary Care Provider Blood Pressure Management

Participant will follow up as would normally do with primary care provider for blood pressure management.

Eligibility Criteria

Inclusion Criteria:

- Acute ischemic stroke in the past 180 days of screening

- Age >/= 18 years old

- Automated Office Blood Pressure ≥135 systolic or ≥85 diastolic at time of screening

- Stage 2 hypertension (as defined by >140 mmHg SBP and or >90 mmHg DBP on 2 occasions
or history of hypertension prior to stroke or currently taking antihypertensive

- Able to live independently (as defined by modified Rankin scale score of 0-2)

Exclusion Criteria:

- CKD stage IV or greater (GFR < 30)

- Inability to check BP in either arm (e.g. amputation, lymphedema)

- Pregnancy

- High-grade intracranial or extracranial stenosis requiring a higher BP goal

- Unable to provide informed consent for themselves in English or Spanish

- Life expectancy less than 12 months

Eligibility Gender
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
United States

Medstar Georgetown University Hospital
Washington, District of Columbia, United States

Investigator: Mary Carter Denny
Contact: 202-444-8532


Mary Carter Denny, MD

Medstar Health Research Institute
NCT Number
Blood Pressure
Blood Pressure Monitor
Home Blood Pressure Monitor
Ischemic Stroke
Stroke Prevention
MeSH Terms
Ischemic Stroke