Prospective cohort study investigating the menstrual cycle phase (MCP) dependent sleepdisordered breathing (SDB) in women travelling to 3600 m.
Not Provided
Other: Exposure to 3600 m
Participants will travel to and stay for 2 nights at an altitude of 3600 m.
Criteria: Inclusion Criteria:
- Healthy, non-smoking women, age 18-44 years, without any diseases and need of
regular medication (including oral contraceptives).
- BMI >18 kg/m2 and <30 kg/m2
- Born, raised and currently living at altitudes <1000 m
- Written informed consent
- Premenopausal, eumenorrheic cycle
Exclusion Criteria:
- Other types of contraceptives (hormonal intrauterine device, vaginal ring,
subcutaneous injections or implants, among others)
- Pregnancy or nursing
- Anaemic (haemoglobin concentration <10g/dl)
- Any altitude trip <4 weks before the study
- Allergy to acetazolamide and other sulfonamides
National Center for Cardiology and Internal Medicine
Bishkek 1528675, Gorod Bishkek 1528334, Kyrgyzstan
Investigator: Talant M Sooronbaev, MD
Contact: +996 312 625679
Sooronbaev@yahoo.com
Michael Furian, Prof. Dr.
+41794037586
michael.furian@usz.ch
Talant Sooronbaev, Prof. Dr.
+996772574567
sooronbaev@yahoo.ru