Official Title
HighCycle Study: Effect of High Altitude on Acute Mountain Sickness in Women Related to Their Menstrual Cycle Phase: A Prospective Cohort Study at 3600 m
Brief Summary

Prospective cohort study investigating the menstrual cycle phase (MCP)-dependentincidence of acute mountain sickness (AMS) in women travelling to 3600 m.

Detailed Description

Not Provided

Recruiting
Acute Mountain Sickness

Other: Exposure to 3600 m

Participants will travel to and stay for 2 days at an altitude of 3600 m.

Eligibility Criteria

Inclusion Criteria:

- Healthy, non-smoking women, age 18-44 years, without any disease and need of regular
medication (including oral contraceptives).

- BMI >18 kg/m2 and <30 kg/m2

- Born, raised and currently living at altitudes <1000 m

- Written informed consent

- Premenopausal, eumenorrheic cycle

Exclusion Criteria:

- Other types of contraceptives (hormonal intrauterine device, vaginal ring,
subcutaneous injections or implants, among others)

- Pregnancy or nursing

- Anaemic (haemoglobin concentration <10g/dl)

- Any altitude trip <4 weks before the study

- Allergy to acetazolamide and other sulfonamides

Eligibility Gender
Female
Eligibility Age
Minimum: 18 Years ~ Maximum: 44 Years
Countries
Kyrgyzstan
Locations

National Center for Cardiology and Internal Medicine
Bishkek 1528675, Gorod Bishkek 1528334, Kyrgyzstan

Investigator: Talant M Sooronbaev, MD
Contact: +996 312 625679
Sooronbaev@yahoo.com

Contacts

Michael Furian, Prof. Dr.
+41794037586
michael.furian@usz.ch

Talant Sooronbaev, Prof. Dr.
+996772574567
sooronbaev@yahoo.ru

University of Zurich
NCT Number
Keywords
women
Hypoxia
prevention
Acetazolamide
Altitude
MeSH Terms
Altitude Sickness
Hypoxia