Using the data from the HelP study, the underlying processes of the diseases ME/CFS andPAIS are to be researched and elucidated. The comparison of affected patients withhealthy controls is intended to identify disease-specific patterns that could be relatedto the development or progression of the disease. The aim is to find a suitable biomarkerfor diagnostics and to develop therapeutic approaches.
The underlying pathomechanisms of the diseases PAIS and ME/CFS are to be investigated and
elucidated in more detail. The aim is to establish a cohort of healthy controls at our
MRI Chronic Fatigue Center (MCFC). Within this cohort, the measurement instruments used
so far in ME/CFS diagnostics will be validated. In addition, data material from this pool
should be used for the statistical evaluations of various case-control studies of our
center and our cooperation partners in order to find and develop a suitable biomarker for
diagnostics and therapeutic approaches for PAIS and ME/CFS.
Diagnostic Test: Diagnostic Test
The following clinical data sources are used:
- Personal interview (anamnesis)
- Physical examination
- Questionnaires
- Functional assessment
- Imaging techniques
The following biological materials are used:
• Max. 30 ml of blood
Inclusion Criteria:
- Healthy control subjects without a known medical diagnosis, except: asthma,
allergies, neurodermatitis, if this does not require regular medication
(self-disclosure)
- Age: 10 - 25 years
- Written declaration of consent or, in the case of minors, written declaration of
consent from the participants and their legal representatives
Exclusion Criteria:
- Acute illnesses (e.g. infections) or major injuries
- Known chronic diseases (including psychological diagnoses) other than those
mentioned above
- Surgery or blood transfusion in the last 3 months
- No intake of on-demand medication (e.g. painkillers) in the last 7 days before the
date of the examination
- Pregnancy; Breastfeeding
- Limited legal capacity
Not Provided
Prof. Dr. med. Uta Behrends
+49 89 3068 2793
uta.behrends@mri.tum.de
Not Provided