At the moment, the number of people with long COVID is unkown because there is still noeffective diagnosis. This is why is very important to analyze the most common symptoms,which are: depression, anxiety and fatigue. This project seeks to analyze some bloodcomponents of people with long COVID, such as microRNAs and vitamin B12, in order toidentify the body processes that changed after COVID-19 and thereby design bettertherapies and diagnostic methods focused on each of them.The hypothesis is that the expression of miR-21, -146a and -155 will be overexpressed aswell as there will be a deficiency of vitamin B12 in serum in subjects suffering fromlong COVID with neurological symptoms of depression, anxiety and fatigue.
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Inclusion Criteria:
- Subjects with confirmed diagnosis of COVID-19 by SARS-CoV-2 infection by PCR or
antigen testing.
- With presence of neurological symptoms of depression, anxiety and fatigue associated
with COVID-19 after three months from the first day of acute infection symptoms.
Exclusion Criteria:
- Subjects who have presented symptoms of acute infection in the last twelve weeks.
- Subjects who present diagnostic premorbid neurological alterations.
- Subjects who do not have at least 2 doses of COVID-19 vaccine, with last application
date equal or older than 3 months.
Instituto Nacional de Rehabilitación
Ciudad de México, Mexico
Investigator: Alfonso Alfaro Rodriguez, Doctorado
Contact: 55 5999 1000
alfa1360@yahoo.com.mx
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