Postoperative pain is important for patient comfort, wound healing and earliermobilisation. Different procedures are used by clinicians for this purpose. Intravenousand regional anaesthesia techniques can be used for this purpose in patients undergoinglaparoscopic cholecystectomy.
In our study, the investigators aimed to investigate the effectiveness of different
methods applied for post-operative pain in patients undergoing laparoscopic
cholecystectomy surgery.
Procedure: M-TAPA block
ultrasound guided Modified thoracoabdominal nerves block through perichondrial
approach(M-TAPA) block (0.3 ml/kg , %0.25 bupivacaine) will be performed
Procedure: EXORA block
Ultrasound guided External Oblique And Rectus Abdominis Plane (EXORA) Block block (0.3
ml/kg , %0.25 bupivacaine) will be performed
Drug: Tramadol
400 mg tramadol, IV 4 mg/ mL tramadol solution into 100 mL normal saline;
Patient-controlled analgesia settings: 0.3 mg/kg bolus, 10 mg Demand dose and 20 min lock
out interval, six-hour limit infusion to attain 100 mg. Maximum daily dose was set at 400
mg.
Inclusion Criteria:
- laparoscopic cholecystectomy surgery
  -  Patients with ASA (American Society of Anaesthetists) scores I and III will be
     included.
Exclusion Criteria:
- Uncontrolled Arterial Hypertension
- Uncontrolled Diabetes Mellitus,
- Mental retardation ,
- Antidepressant use
- Metabolic disorders,
- Bleeding diathesis
- Patients with a body mass index above 30.
Bursa Yuksek Ihtisas Training and Research Hospital
Bursa	750269, Turkey (Türkiye)
Korgün Ökmen, Principal Investigator
 Bursa Yuksek Ihtisas Training and Research Hospital