Official Title
Randomized Controlled Trial Evaluating the Effectiveness of a Breathing Control Technique on Long COVID Symptoms at the Reunion University Hospital
Brief Summary

Despite the controversy, on October 6, 2021, the World Health Organization (WHO)recognized Long Coronavirus disease (COVID) by officially defining it: " symptomsappeared 3 months after the onset of the primary infection by the Severe AcuteRespiratory Syndrome Coronavirus-2 (SARS-CoV-2), persisting for at least 2 months andwhich cannot be explained by any other condition ". Long COVID can affects any type ofpatient and has polymorphic and fluctuating symptoms over time.The Reunion Island is a French overseas department located in the Indian Ocean accountingmore than 860,000 inhabitants. It has recorded since March 11, 2020, nearly 491,825 casesof COVID-19 and 961 deaths of hospitalized patients. Reunion's population is multi-ethnicand younger than the metropolitan France's one. It also has a higher prevalence ofobesity and type 2 diabetes, two serious form factors of COVID-19. This specific contextmakes this island a particular study site for Severe Acute Respiratory SyndromeCoronavirus-2 (SARS-CoV-2) and Long COVID.In addition, some studies have confirmed the involvement of the autonomic nervous system(ANS) in the symptomatology of Long COVID and demonstrated that patients with a LongCOVID present a dysfunction of their ANS which is objectified by a reduced Heart RateVariability (HRV). The regulation of heart rate by the ANS is strongly favored byrespiration. A regular slow and deep breathing training helps to adjust the baroreflex,which connect heart rate, breathing and blood pressure. The result of this training is aninduced state called "cardiac coherence" (CC).The investigator therefore hypothesize that respiratory training to CC could "re-educate"the ANS and durably improve the symptomatology of patients with Long COVID.

Detailed Description

Not Provided

Not yet recruiting
Long Covid

Other: Cardiac coherence

Use of Cardiac coherence (complementary respiratory training) during 6 month

Eligibility Criteria

Inclusion Criteria:

- Patients over the age of 18,

- living in Reunion and

- having a diagnosis of Long COVID according to the World Health Organization (WHO)
definition will be included in this study.

- These patients must attest to their primary infection with Severe Acute Respiratory
Syndrome Coronavirus-2 (SARS-CoV-2) and present a negative antigen test at the time
of inclusion.

Exclusion Criteria:

Patients:

- with a chronic or disabling respiratory pathology preventing respiratory training
(asthma, Chronic Obstructive Pulmonary Disease (COPD), active tuberculosis,
pulmonary sequelae of COVID-19, etc.) practicing or having practiced a regular
respiratory control technique (yoga, Cardiac coherence training, etc.) in the last 6
months

- taking a beta-blocker, betamimetic, anti-arrhythmic, morphine, antidepressant
treatment (Escitalopram)

- having a pacemaker or severe heart disease

- Current and known pregnancy or breastfeeding woman

- with a cognitive deficit

- under guardianship/curators or under judicial protection

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
Countries
France
Locations

CHU de la Réunion
Saint-Denis, France

CHU de la Réunion
Saint-Pierre, France

Contacts

Léa BRUNEAU
02 62 90 68 83 - +262
lea.bruneau@chu-reunion.fr

Not Provided

Centre Hospitalier Universitaire de la Réunion
NCT Number
MeSH Terms
Post-Acute COVID-19 Syndrome