The aim of this study is to evaluate whether there are chronic effects in the pulmonarysystem and systemic level in individuals in the post COVID19 period in order to elucidatethe involvement of inflammation after recovery. In addition, a perspective on the utilityof pulmonary function testing and pulmonary ultrasound in the evaluation of chroniceffects and patient follow-up will is aimed to be provided. By measuring the proteinlevels of inflammatory markers along with the data abovementioned, a foresight regardingthe long-term effects of the previous infection at both functional and immunologicallevels will be obtained, allowing us to evaluate the post-COVID period from differentangles.Volunteers who recovered from COVID-19 and those who didn't have COVID-19 were comparedby evaluating chest x-ray scores (CXR), lung ultrasound scores (LUSS), pulmonary functiontests and inflammatory cytokine levels (TNF-α, IL-1, IL-6, IL-17A).
Objective: The aim of this study is to evaluate whether there are chronic effects in the
pulmonary system and systemic level in individuals in the post COVID19 period in order to
elucidate the involvement of inflammation after recovery. In addition, a perspective on
the utility of pulmonary function testing and pulmonary ultrasound in the evaluation of
chronic effects and patient follow-up will is aimed to be provided. By measuring the
protein levels of inflammatory markers along with the data abovementioned, a foresight
regarding the long-term effects of the previous infection at both functional and
immunological levels will be obtained, allowing us to evaluate the post-COVID period from
different angles.
Materials and Methods: Volunteers who recovered from COVID-19 infection at least 3 months
or more were included in the study, while healthy volunteers who did not have the
infection were enrolled as the control group. Two groups were compared by evaluating
chest x-ray scores (CXR), lung ultrasound scores (LUSS), pulmonary function tests and
inflammatory cytokine levels (TNF-α, IL-1, IL-6, IL-17A).
Diagnostic Test: Pulmonary Ultrasound, Respiratory Function Test
Volunteers underwent pulmonary ultrasound and respiratory function test
Inclusion Criteria:For the control group;
- Age range: 18-60 years old
- Not having had COVID-19 infection
- (For female patients) No pregnancy or puerperium
- Consent for the study
- To be able to complete the pulmonary function test successfully
- Vital signs at the stage of lung ultrasound or pulmonary function testing during the
study no change in findings
- Not having an active infection at the time of the workplace examination
- No abnormal findings in the chest radiograph taken before the study
- Absence of existing autoimmune or rheumatological disorders For the experimental
group;
- Age range: Being between 18-60 years old
- Having had COVID-19 infection and post infectious period of 3 months or more to be
- (For female patients) No pregnancy or puerperium
- Consent for the study
- To be able to complete the pulmonary function test successfully
- Vital signs at the stage of lung ultrasound or pulmonary function testing during the
study no change in findings
- Not having an active infection at the time of the workplace examination
- Abnormal findings on chest radiography taken in the pre-infectious period before the
study absence of
- Absence of existing autoimmune or rheumatological disorders
Exclusion Criteria:
- Age range: Being outside the 18-60 age range
- (for the experimental group) COVID-19 infection and 3 days of post infectious period
under the month
- (For female patients) Pregnancy or puerperium
- Lack of consent for the study
- Failure to complete the pulmonary function test (dizziness, incompatibility, etc.)
reasons)
- Vital signs at the stage of lung ultrasound or pulmonary function testing during the
study change in findings
- Having an active infection at the time of the workplace examination
- Abnormal chest radiographs taken in the pre-infectious period before the study the
presence of findings
- Existing autoimmune or rheumatological disease
Yeditepe University
Istanbul 745044, Turkey (Türkiye)
Not Provided