2. Participants will: - Take nitazoxanide 600mg (or placebo) orally twice daily for 7 days, for a total of 14 doses. - Visit the clinic on the 7th day of treatment for a check-up and safety tests. - Keep a diary of their symptoms and other medications used
Not Provided
Drug: Nitazoxanide 600Mg Oral Tablet / placebo oral tablet
1 tablet every 12 hours
Inclusion Criteria:
- Signed informed consent form;
- Male or female;
- Age ≥ 18 years;
- COVID-19 or influenza diagnosed by rapid test, with symptom onset less than 48 hours
ago;
- Clinical condition compatible with outpatient treatment.
Exclusion Criteria:
- Known hypersensitivity to nitazoxanide;
- History of cardiomyopathies, hepatopathies, or nephropathies;
- Antineoplastic treatment with chemotherapy or radiotherapy;
- Severe autoimmune diseases with immunosuppression;
- Transplant recipients;
- Any uncompensated systemic disease at the investigator's discretion;
- Participation in clinical studies in the last 12 months;
- Pregnant or breastfeeding individuals;
- Suspected bacterial coinfection or prescription of antibiotic therapy at enrollment;
- Diagnosis of neurological disease (traumatic brain injury, stroke, Parkinson's
disease, Alzheimer's disease, other dementias);
- Diagnosis of developmental disorder (ADHD, ASD, learning disabilities, intellectual
disability, Rett syndrome);
- Significant hearing or vision impairment.
Not Provided
Not Provided