This is a national multicenter, prospective, observational study. It is planned to enroll1215 patients with newly diagnosed essential hypertension in 80 centers, and divide theminto 3 groups according to different treatment plans given by doctors: AZL-M monotherapygroup, CCB monotherapy group (amlodipine besylate tablets or nifedipinecontrolled-release tablets) and AZL-M+CCB (amlodipine besylate tablets or nifedipinecontrolled-release tablets) combined treatment group. Subjects were visited 4 times atbaseline, 1 month, 3 months, and 6 months, and the following key indicators of subjectswere measured according to the doctor's decision, and the measurement results werecollected
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Drug: Azilsartan Medoxomil Potassium Tablet
Azilsartan Medoxomil Potassium Tablet，80mg，qd，lasts six month
Drug: Nifedipine Sustained -release Tablets
Nifedipine Sustained -release Tablets，qd，The maximum clinical dose，lasts six months；
Drug: Levoamlodipine Maleate Table
Levoamlodipine Maleate Table，qd，The maximum clinical dose，lasts six months；
Inclusion Criteria:
1. Age ≥ 18 years old (one year old);
2. Patients diagnosed with essential hypertension;
3. Did not receive any antihypertensive drug treatment for at least 3 months before
enrollment;
4. Eligible to use 80 mg once-daily AZL-M at baseline or CCB (amlodipine besylate
tablets or nifedipine controlled-release tablets) or CCB (besylate Amlodipine
tablets or nifedipine controlled-release tablets) + AZL-M 80 mg once-daily
combination therapy; Volunteer to participate in this study, understand and sign the
written informed consent.
Exclusion Criteria:
1. Used antihypertensive drugs for indications other than hypertension within 3 months
before enrollment;
2. Has a history of alcoholism, drug abuse or illegal drug use;
3. Pregnant, breastfeeding women, and those who plan to become pregnant in the near
future;
4. Life expectancy is less than one year; Participating in other clinical trials.
Junbo Ge
Shanghai, Shanghai, China
Investigator: Junbo Ge
Jun Bo Ge, academician
+86 13901977506
ge.junbo@zs-hospital.sh.cn
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