The study use a triple blind, placebo-controlled design enrolling male and femalesubjects between 30-70 yo to evaluate the effect of daily consumption of a cacaosupplement on inflammation, endothelial damage, handgrip strength, fatigue scale andquality of life.
The study use a triple blind, placebo-controlled design enrolling male and female
subjects between 30-70 yo distributed homogeneously at random in two groups: the control
group (Placebo) and the intervention group (Cacao Flavonoids) both groups affected for 90
days.
The variables to consider will be: Interleukins (IL-1b, IL-6), Tumoral Necrosis Factor
alpha (TNF-α) and syndecan-1.
For physical performance is evaluated the handgrip strength. The investigators also
assessed quality of life using the Health Related QoL (EQ-5D) questionnaire, and the
numerical fatigue rating scale.
Dietary Supplement: Flavonoids
1 capsule every 12h for 90 days
Other Name: Cacao and Health EC-Fitness
Inclusion Criteria:
- Post-COVID-19 patients, at least 6 months after symptom onset
- Chronic fatigue
Exclusion Criteria:
- Allergy or intolerance caused by active ingredients
- Pregnancy or lactation
- BMI >35
- chronic liver disease
- chronic kidney disease
C.E. Indianilla
Mexico City 3530597, Mexico City 3527646, Mexico
Not Provided