he COVID-19 pandemic had a detrimental global impact on the health of most populations.
It causes and also generates further damage to physiology and psychology. Mindfulness is
recognized as an effective method for improving the symptoms of physical and mental
problems. The purpose of this review will explore the efficacy of an online mindfulness
intervention for individuals or groups that impacted symptoms of physiology and
psychology in adults during the pandemic base on the principle of evidence-based
medicine. At the same time, a set of mindfulness intervention plans will be developed
based on the best evidence searched, and a pilot study will be conducted. Therefore, this
research design will be divided into two stages. In the first stage, six electronic
bibliographic databases will be comprehensively searched for randomized controlled trials
that have been published from February 2020 to currently published articles. The research
subjects are adults who live in the community and accept online mindfulness intervention.
Quality assessment will be performed according to the Cochrane Collaboration's Risk of
Bias tool will be used for randomized controlled clinical trials (RCTs). A meta-analysis
of the intervention timing and measurements will be performed using Review Manager 5.1
software. The second phase will be a randomized controlled trial pilot study of
mindfulness interventions, The research subjects will be divided into two groups, namely
the mindfulness intervention experimental group (E) and the control group (C). The
researcher uses structured questionnaires to collect data before intervention (To) and at
4 weeks (T1), 8 weeks (T2) after the intervention. Data will be analyzed using the
Generalized Estimating Equation to analyze the repeated measurements and
intention-to-treat analysis for reducing attrition bias.