The goal of this clinical trial is to test the efficacy of telerehabilitation practice inLong COVID-19 patients. The main question[s] it aims to answer are whethertelerehabilitation practice in Long COVID-19 patients help to reduce stress oxidative,reduce inflammation, improve functional capacity and improve quality of life.Participants will receive 12 weeks of telerehabilitation practice Researchers willcompare intervention group (that received telerehabilitation) and control group (thatreceived standard treatment) to see if there is better outcome in intervention group.
Study background:
Several study show that some survivors of COVID-19 have post COVID-19 sequelae. Previous
studies suggest that rehabilitation interventions with appropriate prescription of
physical exercise can provide short, medium and long term health benefits.
Telerehabilitation services are an innovative strategy to support rehabilitation
intervention and hopefully able to increase compliance of patients to exercise program.
This study aims to prove the effectiveness of telerehabilitation in improving levels of
inflammation, oxidative stress, functional capacity and quality of life in Long COVID-19
patients. Participants will be divided into intervention group and control group.
Baseline measurement will be taken. Telerehabilitation will be given to the intervention
group for 12 weeks. Control group will receive standard rehabilitation treatment. After
12 weeks post intervention measurement will be taken.
Behavioral: Telerehabilitation
Exercise prescriptions will be given based on the result of baseline assessment. The
intensity of the exercise prescription and level of monitoring will be tailored to each
participant's ability and condition. Exercise will be prescribed by a Physical Medicine
and Rehabilitation specialist in accordance with standard rehabilitation protocols.
Exercise will consist of aerobic exercise, resistance exercise and breathing exercise.
Participants are asked to commit to do at least 36 sessions of exercise. Participants
will be allowed to have a hybrid approach (10-12 in person, 24-26 virtual) or fully
virtual.
Behavioral: Standard rehabilitation care
Exercise prescriptions will be given based on the result of baseline assessment. The
intensity of the exercise prescription and level of monitoring will be tailored to each
participant's ability and condition. Exercise will be prescribed by a Physical Medicine
and Rehabilitation specialist in accordance with standard rehabilitation protocols.
Exercise will consist of aerobic exercise, resistance exercise and breathing exercise.
Participants are asked to commit to do at least 36 sessions of exercise. Participants
will be allowed to have 10-12 in person exercise.
Inclusion Criteria:
- COVID-19 survivors
- Have at least one of the following sequelae:
- fatigue
- dyspnea and/or chronic cough
- joint and/or muscle pain
- headache
- insomnia (difficulty sleeping)
- impaired concentration / memory
- Willing to take part in the telerehabilitation program regularly during the study
- Willing to participate in the research and sign the consent form
Exclusion Criteria:
- Unable to use the mobile phone application and zoom meet
- Unable to come to the hospital for examination or training (if needed)
- Cognitive impairment (MMSE <21)
- Neuromusculoskeletal disorder which will affect rehabilitation interventions
- Severe chronic lung disease
- Severe heart disease (Grade III-IV from the New York Heart Association)
- Chronic kidney disorders
- Malignancy
- Severe autoimmune disease
Fakultas Kedokteran Universitas Indonesia
Jakarta Pusat, DKI Jakarta, Indonesia
Investigator: Nurul Paramita, MD, MBiomed
Contact: 6281281839593
nurul.paramita61@ui.ac.id
Investigator: Nurul Paramita, MD, MBiomed
Nurul Paramita, MD, MBiomed
6281281839593
nurul.paramita61@ui.ac.id
Nurul Paramita, MD, MBiomed, Principal Investigator
Fakultas Kedokteran Universitas Indonesia