Official Title
Effect of Early Implementation of Prone Positioning Among Critically Ill Patients Admitted With Acute Respiratory Distress Syndrome During the COVID-19 Time: A Comparative Retrospective Observational Study
Brief Summary

Background and objective: The ramifications of early lung protective measures and pronepositioning on the ICU length of stay rates of participants admitted to the ICU withacute respiratory distress syndrome amid the COVID-19 pandemic constitute a pivotalexamination. The study aims to identify the effect of early prone positioning on thelength of stay, discharge rate, and number of tracheostomized patients in the ICU.

Detailed Description

Background and objective: The ramifications of early lung protective measures and prone
positioning on the ICU length of stay rates of participants admitted to the ICU with
acute respiratory distress syndrome amid the COVID-19 pandemic constitute a pivotal
examination. The study aims to identify the effect of early prone positioning on the
length of stay, discharge rate, and number of tracheostomized patients in the ICU.

Methodology: This retrospective study was conducted on critically ill patients needing
mechanical ventilation with lung protective strategy and admitted to the Intensive Care
Units of Al-Azhar University Hospitals between March 2020 to April 2022. All patients in
the study were interpreted retrospectively by examining the patient's records. Group A
(n:39) included patients who had been early placed in prone positions within 24 hours of
intubation, and Group B (n:31) included patients who had not been placed in prone
positions. All patients received a lung protective strategy for ARDS. In both groups,
PaO2, PaCo2, PH, SpO2, and PaO2/FiO2 ratio were checked initially and later every 24
hours for 6 days. All patients were evaluated for the total days of both hospital and ICU
length of stay, number of successful discharges to home from the hospital, and the total
number of tracheostomized patients.

Completed
Severe Acute Respiratory Syndrome

Other: PRONE POSITION

early placed in prone positions within 24 hours of intubation

Eligibility Criteria

Inclusion Criteria:

- All patients of both sexes.

- Aged from 18 to 70 years.

- Body Mass Index (BMI) from 25 to 35 kg/m2.

- Critically ill due to ARDS resulting from COVID-19 pneumonia.

Exclusion Criteria:

- Patients who spent more than 24 hours on mechanical ventilators before enrolment in
the study.

- Patients who died within the first 24 hours of presentation.

- Patients with advanced cancer.

- Pregnant patients.

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: 70 Years
Countries
Egypt
Locations

Al-Azhar faculty of medicine
Cairo 360630, Egypt

SAMEH H SEYAM, PHD, Study Chair
Consultant critical care

Al-Azhar University
NCT Number
Keywords
Prone, Lung protective, ARDS, APACHI II, SOFA
MeSH Terms
Severe Acute Respiratory Syndrome
Prone Position