The goal of this clinical trial is to test the effect of Rehacom on depression andQuality of life in post covid -19 patients. The main question it aims to answer is:• Is a cognitive rehabilitation therapy will improve depression and quality of life inpatients with post COVID-19? Researchers will compare Rehacom with exercise therapy tosee if rehacom can improve depression and quality of life in patients with post COVID-19neuropsychological problems.
Purpose of the study:
- To investigate the effect of cognitive rehabilitation therapy on depression in post
COVID-19 patients.
- To investigate the effect of cognitive rehabilitation therapy on quality of life in
post COVID-19 patients.
Significance of the study:
•There is growing evidence that individuals with COVID-19 disease can develop a range of
neurological complications including cognitive and neuropsychiatric symptoms . Cognitive
rehabilitation essential in improving quality of life with Introduction of new
neuropsychological rehabilitation tools based on the latest developments in computer
sciences.
This study aims to investigate the RehaCom as a cognitive rehabilitation program on
depression and quality of life in patients suffer from post COVID-19 neuropsychological
problems.
Behavioral: rehacom
Rehacom was carried out at the cognition laboratory at Faculty of physical therapy, Cairo
University for training of figural memory, attention concentration.
1. Attention concentration training consists of 24 levels of difficulties .
2. Figural memory training consists of 9 levels of difficulties. In the training
session, every patient was starting training from level one and when the patient
successfully finished the level, the training then Progress to the level of
difficulty.
Other Name: cognitive behavioral therapy
Inclusion Criteria:
- All patients will be selected according to following criteria:
1. Patients from both genders (male and female).
2. The age of participants ranged from 30 to 45 years .
3. The patients had score more than 24 according to Mini mental state examination
(MMSE).
4. Patient muscle power not less than grade 3 .
5. Patients are ambulant.
6. Patients with confirmation of previous covid19 infection PCR TEST.
7. Participants were required to live in Egypt during the pre-covid and COVID-19
pandemic.
8. Patients meeting the guide line of world health organization (WHO) of
long/post-covid 19 syndromes.
9. Patients are "long-haulers" those who history of probable or confirmed
SARS-CoV-2 infection; usually within three months from the onset of COVID-19,
and last more than two months
Exclusion Criteria:
- The patients will be excluded if they have any of the following:
1. Patient previously diagnosed with depression and currently taking medication.
2. patient had prior cognitive impairment.
3. Illiterate patients.
4. patient had experienced another major stressful event (e.g., divorce,
bereavement) in the past year.
5. Checking comorbidities (sum of hypertension, diabetes, arrhythmia, myocardial
infarction, Chronic Obstructive Pulmonary Disease/Asthma.
6. Mild cognitive impairment, dementia, other neurodegenerative diseases, stroke,
depression,
7. Osteoarthritis , low back pain and prevalence of polypharmacy (5 or more drugs)
at admission.
Faculty of physical therapy .Cairo university
Cairo, Egypt
Hossam M Mohammed, PHD, Principal Investigator
Cairo University