Official Title
Early-initiated High Flow Oxygen Therapy vs Conventional Oxygen Therapy Among Patients With ARDS in the Course of SARS-CoV2 Pneumonia: Prognosis and Impact on the Respiratory and Cardiovascular Systems.
Brief Summary

The aim of the study is to compare two methods of oxygen therapy in patients with acuterespiratory distress syndrome in the course of SARS-CoV2 pneumonia. The initial method ofoxygen supply during coronavirus pneumonia is conventional oxygen therapy using a facemask or nasal cannula. However, there have been reports in the literature that earlyinitiation of high-flow oxygen therapy with a nasal cannula is associated with betterprognosis. The study we perform is intended to provide reliable evidence for confirmationthis hypothesis.

Detailed Description

Not Provided

Unknown status
Corona Virus Infection
ARDS Due to Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2
Oxygen Deficiency

Device: Oxygen theraphy with high flow nasal cannule

Oxygen theraphy with high flow nasal cannule

Device: Oxygen theraphy with mask with reservoir

Oxygen theraphy with mask with reservoir

Eligibility Criteria

Inclusion Criteria:

1. The diagnosis of a current SARS-CoV2 infection (confirmed RT-PCR test or antigen
test [allowed in Poland, with sensitivity ≥90 and specificity ≥97]);

2. Hospitalization in the Oxygen Sector of the Temporary Hospital in Szczecin;

3. Pneumonia during SARS-CoV2 infection;

4. ARDS (PaO 2 / FiO 2 ratio ≤300);

5. Oxygen flow 8-12 l / min on mask with reservoir and ≤ 60 mmHg paO2 and / or SpO2 <
92%;

6. TNo current indications for treatment in the ICU;

7. Permisson of the patient.

Exclusion Criteria:

1. Probable lack of cooperation with patient;

2. Severe Disease disease, eg generalized neoplastic disease;

3. Concomitant pulmonary diseases (eg, fibrosis lungs);

4. Respiratory acidosis - pH <7.3 with pCO2> 50 mmHg;

5. Disturbances of consciousness - GCS < 12;

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
Countries
Poland
Locations

Oxygen Therapy Sector of Temporary Hospital
Szczecin, Zachodniopomorskie, Poland

Contacts

Wojciech Witkiewicz
+48509082762
witkiewiczwojciech@gmail.com

Not Provided

Pomeranian Medical University Szczecin
NCT Number
Keywords
SARS-CoV2, COVID-19, HFNC, COT, Oxygen therapy.
MeSH Terms
Pneumonia
Coronavirus Infections
Severe Acute Respiratory Syndrome
COVID-19
Hypoxia