A multicenter, open-label, non-interventional study evaluates the safety and tolerabilityof oral Dimolegin® (60 mg once daily) for thromboprophylaxis in hospitalized adults (≥18years) with moderate COVID-19 in real clinical pratice. The primary objective is toassess safety and tolerability of Dimolegin® in preventing thrombotic complications.
Not Provided
Drug: Dimolegin
Dimolegin® is administered orally once daily,The recommended dose is 60 mg (six 10 mg
tablets) once daily.
Inclusion Criteria:
Here's a concise English translation:
- Voluntarily signed informed consent to participate in a non-interventional study.
- Hospitalized patients with moderate COVID-19 requiring anticoagulant therapy for
prevention of thrombotic complications.
- Men and women aged ≥18 years.
- Patients prescribed Dimolegin® 10 mg enteric-coated film tablets for
thromboprophylaxis as part of routine care for moderate COVID-19.
- Ability to understand study requirements, provide written consent and comply with
protocol procedures.
Exclusion Criteria:
- Hypersensitivity to Dimolegin®.
- Clinically significant active bleeding at screening.
- Concomitant therapy with fibrinolytics or other anticoagulants.
- Anemia or thrombocytopenia.
- Thrombophilia.
- Other coagulopathies or contraindications to anticoagulants.
- Liver disease with impaired function or biliary tract disease.
- Creatinine clearance <30 mL/min.
- Gastrointestinal disorders affecting absorption.
- Pregnancy, breastfeeding, suspected pregnancy, or planned pregnancy within 3 months
(including male patients whose partners plan pregnancy).
- Use of investigational or unapproved drugs, or participation in another clinical
study within 90 days before therapy start.
- History or suspicion of alcohol or drug abuse, dependence, or addiction.
- Any other condition that, in the investigator's opinion, could interfere with study
participation or pose undue risk.
Regional Clinical Hospital No. 3
Chelyabinsk 1508291, Russia
Republican Clinical Hospital named after Professor A.F. Agafonov
Kazan' 551487, Russia
Infectious Diseases Clinical Hospital No. 1
Moscow 524901, Russia
Infectious Diseases Hospital No. 2
Sochi 491422, Russia
Tomsk Regional Hospital
Tomsk 1489425, Russia
Regional Infectious Diseases Clinical Hospital
Yaroslavl 468902, Russia
Not Provided