Official Title
Personalized, Scientifically Based Technologies in the Diagnosis and Treatment of SARS-CoV-2 as a Possible Cervical Cancer Risk Factor
Brief Summary

This study aims to evaluate the diagnostic value of an electroacupuncture-based methodfor detecting viral persistence (human papillomavirus and SARS-CoV-2) in patients withcervical cancer. The study investigates whether persistent viral signatures can beidentified through measurable electrodiagnostic responses at acupuncture pointsassociated with organ systems affected by chronic viral infection. The goal is to assessthe feasibility, reproducibility, and potential clinical relevance of this diagnosticapproach in oncology patients.

Detailed Description

This study investigates the diagnostic potential of an electroacupuncture-based
measurement method to detect viral persistence in patients with cervical cancer.
Increasing evidence indicates that oncologic processes may be influenced by chronic viral
activity, including persistent human papillomavirus (HPV) infection and, in some cases,
secondary viral signatures such as SARS-CoV-2. Although HPV is the primary etiologic
agent in cervical cancer, clinical observations suggest that long-term viral presence may
contribute to variations in disease behavior, immune dysfunction, and treatment response.

The diagnostic method used in this study is based on measurement of electrical parameters
at standardized acupuncture points. These points are functionally connected to organ
systems involved in chronic viral disease. Changes in their electrical characteristics
may reflect physiological responses associated with viral persistence. The technique has
been previously developed and refined in clinical practice and has demonstrated
reproducibility in identifying characteristic response patterns in patients with viral
and post-viral conditions.

This study aims to evaluate whether measurable electrodiagnostic responses correlate with
persistent viral signatures in cervical cancer patients. All participants undergo
standardized diagnostic measurements performed under controlled conditions. The study
does not involve therapeutic intervention, drug administration, or device implantation.
Only diagnostic data are collected.

The primary objective is to assess whether this method can reliably identify patterns
consistent with viral persistence. Secondary objectives include evaluating repeatability
of measurements, describing characteristic profiles in this patient population, and
assessing feasibility of integrating this diagnostic approach into clinical oncology
settings.

This research is expected to contribute to a better understanding of viral involvement in
cancer microenvironments and to support the development of non-invasive diagnostic tools
for evaluating viral activity in oncologic patients.

Enrolling by invitation
Cervical Cancer

Diagnostic Test: Electroacupuncture

Non-invasive electrodiagnostic assessment using electroacupuncture measurements to
evaluate bioelectrical response patterns associated with viral markers in patients with
cervical cancer.

Eligibility Criteria

Inclusion Criteria:

- Histologically confirmed cervical cancer (FIGO stage IIIA-IVA)

- Age ≥21 years

- ECOG performance status adequate for diagnostic procedures

- Adequate organ function

- Ability to provide informed consent

Exclusion Criteria:

- Poor renal function (elevated creatinine)

- Significant liver dysfunction (elevated bilirubin or liver enzymes)

- Severe cardiovascular or pulmonary disease

- Pregnancy or breastfeeding

- Severe mental illness or inability to provide informed consent

- Known non-compliance or substance abuse

Eligibility Gender
Female
Eligibility Age
Minimum: 21 Years ~ Maximum: 70 Years
Countries
Uzbekistan
Locations

City Branch of the National Oncology and Radiology Center
Tashkent, Uzbekistan

Not Provided

Oncology Center,Ministry Of Heath,Uzbekistan
NCT Number
Keywords
medicament testing
viral antigen persistance
Human Papillomavirus
MeSH Terms
Uterine Cervical Neoplasms