This study aims to compare the diagnostic accuracy of rapid antigen detection tests(RDTs) for SARS-CoV-2 using nasal swab insertion depths of 2 cm versus 4 cm.The study is an investigator-initiated, randomized clinical trial conducted at a publicCOVID-19 test center in Copenhagen, Denmark.Following enrollment, participants complete a questionnaire regarding symptoms andvaccination status.Participants are randomized in a 1:1 ratio to one of two sampling sequences: either a 2cm swab in the left nostril and a 4 cm swab in the right nostril, or vice versa. Allparticipants undergo a healthcare worker-collected throat swab for RT-PCR analysis, whichserves as the reference standard for SARS-CoV-2 infection.
Not Provided
Diagnostic Test: 4 cm nasal swab - left nostril
a 4 cm nasal swab insertion in the left nostril
Diagnostic Test: 2 cm nasal swab in the left nostril
a 2 cm nasal swab insertion in the left nostril
Diagnostic Test: 4 cm nasal swab - right nostril
a 4 cm nasal swab insertion in the right nostril
Diagnostic Test: 2 cm nasal swab - right nostril
a 2 cm nasal swab insertion in the right nostril
Inclusion Criteria:
- Citizens, aged 16 years or older, showing up for a SARS-CoV-2 RT-PCR test at
Testcenter Valby in Copenhagen, Denmark
Exclusion Criteria:
- non-fluent in Danish
- citizens with nasopharyngeal or oropharyngeal anomalies (e.g. neck breathers with
tracheostomy)
Rigshospitalet
Copenhagen, Denmark
Not Provided