It is planned to include non-pregnant and non-traumatic patients over the age of 18,
diagnosed with COVID-19, who are treated in the Intensive Care Unit of Selcuk University
Hospital. The frailty status will be evaluated by using the clinical frailty scale at the
admission of the patients to the intensive care unit. Evaluation from the patient
himself, if the consciousness of the patients is clear; If not, it will be done near the
patient. Patients will be divided into two groups using the clinical frailty scale (CFS)
as frail if the score is ≥5 and non-fragile if the score is <5. Demographic information
and vaccination status (how many dose and type) will be questioned, SOFA score, APACHE II
score will be recorded. Routine examinations made from the patient file; thorax computed
tomography (CT) imaging, laboratory values, respiratory support information, drug
treatments applied, patient positions will be recorded. Thoracic CT scans severity scores
for each of the five lung lobes: 0 for no involvement (0%), 1 for minimal involvement
(1%-25%), 2 for mild involvement (26-50%), 3 for moderate involvement (51%) -75) and 4
advanced involvement (76-100%). The total severity score will be the sum of the scores of
the five lobes. If the score is ≤10, it will be considered as mild involvement, and if
the score is >10, it will be considered as severe involvement. Laboratory values;
platelet and lymphocyte count, albumin, sodium, ferritin, D-dimer, crp, procalcitonin,
interleukin-6 and glomerular filtration rate values, neutrophil/lymphocyte ratio,
platelet/lymphocyte ratio, CRP/Albumin ratio, arterial blood gas will be recorded.
Whether or not he received respiratory support; type (invasive/non-invasive positive
pressure respiratory support or high-flow nasal oxygen therapy), duration will be
recorded. The use and duration of vasoactive drugs administered, renal replacement
therapy and its durations will be recorded. Patient positions will be recorded as supine,
lateral decubitus, and prone. The length of stay in the intensive care unit and mortality
of the patients will be recorded. Comparisons will be made between frail and non-fragile
groups on all these evaluated parameters.