Official Title
Analysis of the Efficacy and Tolerance of Covid-19 Convalescent Plasma and Monoclonal Antibodies in the Treatment of SARS-Cov2 Infections in Immunocompromised Patients
Brief Summary

Data on the use of convalescent plasma in the treatment of covid-19 are scarce: theresults of randomized studies involving mainly immunocompetent patients aredisappointing, while case series or retrospective data on more selected patients , inparticular immunocompromised patients suggest a benefit in these patients whose clinicalmanifestation seems essentially related to the uncontrolled infection and not thecytokine storm.

Detailed Description

Not Provided

Recruiting
COVID-19 Convalescent Plasma Treatment
Eligibility Criteria

Inclusion criteria:

- Adult patient

- Immunocompromised patient (solid neoplasia, malignant hemopathy, solid organ
transplantation, primary immune deficiency, systemic disease, chronic inflammatory
disease, etc.)

- Hospitalized between 25/02/2020 and 15/01/2023 at HUS, ICANS, CH Colmar and CH
Mulhouse

- Having received curative monoclonal antibody treatment or convalescent plasma
treatment for SARS-Cov2 infection

- Patient who has not expressed, after being informed, his opposition to the reuse of
his data for scientific research purposes.

Exclusion criteria:

- Subject who expressed their opposition to participating in the study

- Subject under guardianship, curatorship or safeguard of justice

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
Countries
France
Locations

Service des Maladies Infectieuses et Tropicales - CHU de Strasbourg - France
Strasbourg, France

Investigator: François DANION, MD
Contact: 33 3 69 55 15 88
francois.danion@chru-strasbourg.fr

Contacts

François DANION, MD
33 3 69 55 15 88
Francois.danion@chru-strasbourg.fr

Not Provided

University Hospital, Strasbourg, France
NCT Number
Keywords
Covid-19
SARS-CoV2
immunosuppression
cytokine
Convalescent plasma
Monoclonal
Antibodies
MeSH Terms
COVID-19