This research aims to explore the relationship between hormonal receptor expression andthe clinical and histopathological characteristics of meningiomas. The underlyinghypothesis is that hormonal receptor expression, as well as the methylation profile oftheir gene promoters, are associated with specific aspects of meningiomas and patients'clinical outcomes. The main objective is to study the correlation between theimmunohistochemical expression of hormonal receptors and clinicopathological data. Thesecondary objectif is to study the correlation between the methylation profile ofhormonal receptor gene promoters and their immunohistochemical expression.
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Inclusion Criteria:
- Patients who underwent surgery for a meningioma at the University Hospital of Nancy
between 2000 and 2022.
Exclusion Criteria:
- Patients who did not express their consent to participate in the study.
- Patients with grade 2 or 3 meningiomas whose samples are no longer available or in
insufficient quantity to perform an immunohistochemical study.
- Patients with grade 1 meningiomas not selected by randomization.
- Patients withdrawing their consent.
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