This study was designed as a single-center retrospective analysis aimed at investigatingwhether COVID-19 infection increases the risk or burden of radiation-induced pneumonitisin breast cancer patients.
This study was designed as a single-center retrospective analysis aimed at investigating
whether COVID-19 infection increases the risk or burden of radiation-induced pneumonitis
in breast cancer patients. Breast cancer patients who underwent radiotherapy at the
Cancer Center of Zhejiang Hospital between January 1, 2021, and June 30, 2024, were
screened for eligibility. Patients who met the inclusion criteria were identified through
the hospital information system, and their clinical records were reviewed. Follow-up was
conducted via telephone interviews.
Other: COVID-19
The COVID-19 infection situation was used as an intervention measure, and the cohort was
divided into groups.
Inclusion Criteria:
1. patients with pathologically or cytologically confirmed primary breast cancer,
2. aged 18 years or older but younger than 80 years,
3. with complete and reliable medical records,
4. for those with COVID-19 infection, documented evidence of a positive test result.
Exclusion Criteria:
1. concomitant pulmonary malignancies,
2. a history of prior thoracic radiotherapy,
3. concurrent pulmonary infections other than COVID-19 during radiotherapy,
4. missing key data with loss to follow-up,
5. or any other condition considered unsuitable for enrollment by the investigators.
Zhejiang Hospital, Department of Oncology, Hangzhou, China, 310030
Hangzhou 1808926, Zhejiang 1784764, China
Investigator: Pengyuan Liu
Contact: 18368846455
oncologyliupengyuan@outlook.com
Pengyuan Liu
18368846455
oncologyliupengyuan@outlook.com
Not Provided